Some transformations of (-)-(1S,4R)-1-vinyl-7,7-dimethyl-bicyclo[2.2.1]heptan-2-one

被引:4
|
作者
Vostrikov, NS [1 ]
Abutkov, AV [1 ]
Miftakhov, MS [1 ]
机构
[1] Russian Acad Sci, Ufa Sci Ctr, Inst Organ Chem, Ufa 450054, Russia
关键词
D O I
10.1023/A:1013180012045
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Reactions were studied of (-)-(1S,4R)-1-vinyl-7,7-dimethylbicyclo[2.2.1]heptan-2-one with ethyl acetate lithium derivative, potassium acetylide, ozone, with a system OsO4-N-methylmorpholine N-oxide, and some subsequent transformations of the products obtained.
引用
收藏
页码:1102 / 1106
页数:5
相关论文
共 50 条
  • [21] Specificity of the reaction of (−)-1-{(1S,2R,4R)-1-ethenyl-2-hydroxy-7,7-dimethylbicyclo[2.2.1]hept-2-yl}xethanone with ethenylmagnesium bromide
    N. S. Vostrikov
    V. Z. Vasikov
    M. S. Miftakhov
    Russian Journal of Organic Chemistry, 2006, 42 : 962 - 965
  • [22] First Stereoselective Synthesis of (1R,2R,4R)- and (1S,2R,4S)-2-Substituted-1-azabicyclo[2.2.1]heptanes
    Etayo, Pablo
    Badorrey, Ramon
    Diaz-de-Villegas, Maria D.
    Galvez, Jose A.
    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2009, 2009 (09) : 1372 - 1376
  • [23] (1S, 4R)-1,2,3,4,7,7-hexachloro-5,6-bis(chloromethyl)bicyclo[2.2.1]hepta-2,5-diene
    Wilson, Zakiya S.
    Davila, Alfonso
    McLaughlin, Mark L.
    Watkins, Steven F.
    Fronczek, Frank R.
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2007, 63 : O303 - O305
  • [24] (1R,4R,7S)-1,7-dimethyl-7-(phenylsulfonylmethyl)spiro[bicyclo[2.2.1]heptane-2,2′-1,3-dioxolane]
    Wang, Ya-Wen
    Peng, Yu
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2008, 64 : O57 - U3009
  • [25] STEREOSELECTIVE PREPARATION OF (1S,2R)-2-HYDROXY-7,7-DIMETHYLBICYCLO[2.2.1]HEPTANE-1-CARBOXYLIC AND (1S,2S)-2-HYDROXY-7,7-DIMETHYLBICYCLO[2.2.1]HEPTANE-1-CARBOXYLIC ACID
    ISHIZUKA, T
    KIMURA, K
    ISHIBUCHI, S
    KUNIEDA, T
    CHEMICAL & PHARMACEUTICAL BULLETIN, 1990, 38 (06) : 1717 - 1719
  • [26] Discovery of a Potent, Orally Active 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor for Clinical Study: Identification of (S)-2-(1S,2S,4R)-Bicyclo[2.2.1]heptan-2-ylamino)-5-isopropyl-5-methylthiazol-4(5H)-one (AMG 221)
    Veniant, Murielle M.
    Hale, Clarence
    Hungate, Randall W.
    Gahm, Kyung
    Emery, Maurice G.
    Jona, Janan
    Joseph, Smriti
    Adams, Jeffrey
    Hague, Andrew
    Moniz, George
    Zhang, Jiandong
    Bartberger, Michael D.
    Li, Vivian
    Syed, Rashid
    Jordan, Steven
    Komorowski, Renee
    Chen, Michelle M.
    Cupples, Rod
    Kim, Ki Won
    St Jean, David J., Jr.
    Johansson, Lars
    Henriksson, Martin A.
    Williams, Meredith
    Vallgarda, Jerk
    Fotsch, Christopher
    Wang, Minghan
    JOURNAL OF MEDICINAL CHEMISTRY, 2010, 53 (11) : 4481 - 4487
  • [27] SYNTHESIS OF (1R,4R)-2,5-DIAZABICYCLO[2.2.1]HEPTANES AND (1S,4S)-2,5-DIAZABICYCLO[2.2.1]HEPTANES AND THEIR N-SUBSTITUTED DERIVATIVES
    JORDIS, U
    SAUTER, F
    SIDDIQI, SM
    KUENBURG, B
    BHATTACHARYA, K
    SYNTHESIS-STUTTGART, 1990, (10): : 925 - 930
  • [28] (1S,5R)-6,6-Dimethyl-4-(((1S,2S,5S)-2,6,6-trimethyl-4-oxobicyclo[3.1.1]heptan-2-yl)methyl)bicyclo[3.1.1]hept-3-en-2-one
    Ardashov, Oleg V.
    Korchagina, Dina V.
    Bagryanskaya, Irina Yu.
    Volcho, Konstantin P.
    Salakhutdinov, Nariman F.
    MOLBANK, 2022, 2022 (04)
  • [29] PREPARATION OF (-)-(1S,4R)-CAMPHANOYL CHLORIDE [2-OXABICYCLO[2.2.1]HEPTANE-1-CARBONYL CHLORIDE, 4,7,7-TRIMETHYL-3-OXO, (1S)-]
    KAPPES, D
    GERLACH, H
    SYNTHETIC COMMUNICATIONS, 1990, 20 (04) : 581 - 587
  • [30] Regio- and stereoselective synthesis of (1R, 2S, 4R)-5,5-difluorobicyclo[2.2.1]-heptan-2-amine
    Li, Aiwen
    Fotsch, Christopher H.
    St Jean, David J., Jr.
    Yuan, Chester
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2006, 231