Pulmonary Hypertension - Prevalence, Risk Factors, and Its Association with Vascular Calcification in Chronic Kidney Disease and Hemodialysis Patients
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作者:
Nithiya, N.
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Sri Ramachandra Inst Higher Educ & Res, Dept Nephrol, Chennai 600116, Tamil Nadu, IndiaSri Ramachandra Inst Higher Educ & Res, Dept Nephrol, Chennai 600116, Tamil Nadu, India
Nithiya, N.
[1
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Indhumathi, Elayaperumal
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Sri Ramachandra Inst Higher Educ & Res, Dept Nephrol, Chennai 600116, Tamil Nadu, IndiaSri Ramachandra Inst Higher Educ & Res, Dept Nephrol, Chennai 600116, Tamil Nadu, India
Indhumathi, Elayaperumal
[1
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Jagadeswaran, Dhakshinamoorty
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Sri Ramachandra Inst Higher Educ & Res, Dept Nephrol, Chennai 600116, Tamil Nadu, IndiaSri Ramachandra Inst Higher Educ & Res, Dept Nephrol, Chennai 600116, Tamil Nadu, India
Jagadeswaran, Dhakshinamoorty
[1
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Jayaprakash, Varadharajan
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Sri Ramachandra Inst Higher Educ & Res, Dept Nephrol, Chennai 600116, Tamil Nadu, IndiaSri Ramachandra Inst Higher Educ & Res, Dept Nephrol, Chennai 600116, Tamil Nadu, India
Jayaprakash, Varadharajan
[1
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Jayakumar, Matcha
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Sri Ramachandra Inst Higher Educ & Res, Dept Nephrol, Chennai 600116, Tamil Nadu, IndiaSri Ramachandra Inst Higher Educ & Res, Dept Nephrol, Chennai 600116, Tamil Nadu, India
Jayakumar, Matcha
[1
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机构:
[1] Sri Ramachandra Inst Higher Educ & Res, Dept Nephrol, Chennai 600116, Tamil Nadu, India
Pulmonary hypertension (PHTN) is a recently recognized complication in dialysis and it is associated with a poor outcome. We estimated the prevalence of PHTN and its association with vascular calcification in chronic kidney disease (CKD) and hemodialysis (HD) patients. One hundred and thirteen adult CKD patients were included in this study, of which 56 (49.6%) were on conservative treatment (nondialysis group) and 57 (50.4%) were on maintenance HD (dialysis group). Demographic, clinical, and biochemical parameters were collected and compared between the groups. Thirty-nine (69.6%) and 33 (57.8%) males were included in nondialysis and dialysis group, respectively. Mean age was 47.5 +/- 13.7 in nondialysis group and 52.8 +/- 13.9 in the dialysis group. PHTN was estimated using Doppler echocardiography and peripheral vascular calcification by lateral lumbar X-ray with aortic calcification scoring. Patients with and without PHTN and vascular calcification in dialysis and nondialysis group were compared. PHTN was found in 55 patients (48.7%) and it was high in patients on dialysis compared to nondialysis(59.6% vs. 37.5%, P <0.019). Abdominal aortic calcification was present in 35 patients (30.9%), dialysis versus nondialysis group was 22.8% and 39.3%. Increased left atrial diameter was significantly associated with PHTN (P <0.003), whereas peripheral artery calcification was not related to PHT (P = 0.248). The prevalence of PHTN in CKD was 48.7% which was higher in dialysis group than non dialysis group. Increased left atrial (LA) diameter was associated with PHTN but not peripheral arterial calcification.
机构:
Pingtung Christian Hosp, Div Nephrol, Dept Internal Med, Pingtung, TaiwanPingtung Christian Hosp, Div Nephrol, Dept Internal Med, Pingtung, Taiwan
Hsu, Liping
Hsieh, Chin Wen
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Pingtung Christian Hosp, Div Nephrol, Dept Internal Med, Pingtung, Taiwan
Kaohsiung Med Univ, Grad Inst Med, Coll Med, Kaohsiung, TaiwanPingtung Christian Hosp, Div Nephrol, Dept Internal Med, Pingtung, Taiwan
机构:
Jules Verne Univ Picardy Amiens, INSERM, U1088, Amiens, France
Amiens Univ Hosp, Clin Res Ctr, Amiens, France
Amiens Univ Hosp, Div Clin Pharmacol, Amiens, France
Jules Verne Univ Picardy, Amiens, FranceJules Verne Univ Picardy Amiens, INSERM, U1088, Amiens, France
Temmar, Mohamed
Renard, Cedric
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Amiens Univ Hosp, Div Radiol, Amiens, FranceJules Verne Univ Picardy Amiens, INSERM, U1088, Amiens, France
Renard, Cedric
Choukroun, Gabriel
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Jules Verne Univ Picardy Amiens, INSERM, U1088, Amiens, France
Amiens Univ Hosp, Div Nephrol, Amiens, FranceJules Verne Univ Picardy Amiens, INSERM, U1088, Amiens, France
Choukroun, Gabriel
Massy, Ziad A.
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Jules Verne Univ Picardy Amiens, INSERM, U1088, Amiens, France
Univ Paris Ouest Versailles St Quentin En Yveline, Ambroise Pare Univ Hosp, AP HP, Div Nephrol, Boulogne, FranceJules Verne Univ Picardy Amiens, INSERM, U1088, Amiens, France
机构:
Univ Fed Sao Paulo, Escola Paulista Enfermagem, Sao Paulo, SP, Brazil
Univ Araraquara, Araraquara, SP, Brazil
Ctr Univ Estacio Ribeirao Preto, Ribeirao Preto, SP, BrazilUniv Fed Sao Paulo, Escola Paulista Enfermagem, Sao Paulo, SP, Brazil
Ferreira, Viviane
da Fonseca, Cassiane Dezoti
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Univ Fed Sao Paulo, Escola Paulista Enfermagem, Sao Paulo, SP, BrazilUniv Fed Sao Paulo, Escola Paulista Enfermagem, Sao Paulo, SP, Brazil
da Fonseca, Cassiane Dezoti
Bollela, Valdes Roberto
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Univ Sao Paulo, Fac Med Ribeirao Preto, Dept Clin Med, Div Molestias Infecciosas & Trop, Ribeirao Preto, SP, BrazilUniv Fed Sao Paulo, Escola Paulista Enfermagem, Sao Paulo, SP, Brazil
Bollela, Valdes Roberto
Roma, Elen Almeida
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Univ Sao Paulo, Fac Med Ribeirao Preto, Dept Clin Med, Div Nefrol, Ribeirao Preto, SP, BrazilUniv Fed Sao Paulo, Escola Paulista Enfermagem, Sao Paulo, SP, Brazil
Roma, Elen Almeida
Cardeal da Costa, Jose Abrao
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Univ Sao Paulo, Fac Med Ribeirao Preto, Dept Clin Med, Div Nefrol, Ribeirao Preto, SP, BrazilUniv Fed Sao Paulo, Escola Paulista Enfermagem, Sao Paulo, SP, Brazil
Cardeal da Costa, Jose Abrao
Lopes de Sousa, Alvaro Francisco
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Univ Fed Sao Paulo, Escola Paulista Enfermagem, Sao Paulo, SP, Brazil
Univ Nova Lisboa, Inst Higiene & Med Trop, Lisbon, Portugal
Conselho Nacl Desenvolvimento Cient & Tecnol CNPq, Brasilia, DF, BrazilUniv Fed Sao Paulo, Escola Paulista Enfermagem, Sao Paulo, SP, Brazil
Lopes de Sousa, Alvaro Francisco
Barbosa, Dulce Aparecida
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Univ Fed Sao Paulo, Escola Paulista Enfermagem, Sao Paulo, SP, BrazilUniv Fed Sao Paulo, Escola Paulista Enfermagem, Sao Paulo, SP, Brazil
机构:
Gr T Popa Univ Med & Pharm, Clin Nephrol, CI Parhon Univ Hosp, Iasi 700503, RomaniaGr T Popa Univ Med & Pharm, Clin Nephrol, CI Parhon Univ Hosp, Iasi 700503, Romania
Covic, Adrian
Kanbay, Mehmet
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Fatih Univ, Sch Med, Nephrol Sect, Dept Internal Med, Ankara, TurkeyGr T Popa Univ Med & Pharm, Clin Nephrol, CI Parhon Univ Hosp, Iasi 700503, Romania
Kanbay, Mehmet
Voroneanu, Luminita
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Gr T Popa Univ Med & Pharm, Clin Nephrol, CI Parhon Univ Hosp, Iasi 700503, RomaniaGr T Popa Univ Med & Pharm, Clin Nephrol, CI Parhon Univ Hosp, Iasi 700503, Romania
Voroneanu, Luminita
Turgut, Faruk
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Fatih Univ, Sch Med, Nephrol Sect, Dept Internal Med, Ankara, TurkeyGr T Popa Univ Med & Pharm, Clin Nephrol, CI Parhon Univ Hosp, Iasi 700503, Romania
Turgut, Faruk
Serban, Dragomir N.
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Gr T Popa Univ Med & Pharm, Dept Physiol, Iasi 700115, Romania
Gr T Popa Univ Med & Pharm, Unit Cell Physiol & Pharmacol, Ctr Study & Therapy Pain, Iasi 700454, RomaniaGr T Popa Univ Med & Pharm, Clin Nephrol, CI Parhon Univ Hosp, Iasi 700503, Romania
Serban, Dragomir N.
Serban, Ionela Lacramioara
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Gr T Popa Univ Med & Pharm, Dept Physiol, Iasi 700115, Romania
Gr T Popa Univ Med & Pharm, Unit Cell Physiol & Pharmacol, Ctr Study & Therapy Pain, Iasi 700454, RomaniaGr T Popa Univ Med & Pharm, Clin Nephrol, CI Parhon Univ Hosp, Iasi 700503, Romania
Serban, Ionela Lacramioara
Goldsmith, David J.
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Guys Hosp, Renal Unit, London SE1 9RT, EnglandGr T Popa Univ Med & Pharm, Clin Nephrol, CI Parhon Univ Hosp, Iasi 700503, Romania