Ultrasmall iron oxide nanoparticles: Synthesis, physicochemical, and magnetic properties

被引：7

作者：

Bae, Sung-Jin ^{[2
,3
]}

Park, Ji-Ae ^{[3
]}

Lee, Jae-Jun ^{[3
]}

Lee, Gang-Ho ^{[4
]}

Kim, Tae-Jeong ^{[5
]}

Yoo, Done-Sik ^{[6
]}

Chang, Yongmin ^{[1
]}

机构：

[1] Kyungpook Natl Univ, Dept Diagnost Radiol & Mol Med, Taegu 702701, South Korea

[2] Keimyung Univ, Dongsan Med Ctr, Dept Radiol, Daegu 700712, South Korea

[3] Kyungpook Natl Univ, Dept Med & Biol Engn, Taegu 702701, South Korea

[4] Kyungpook Natl Univ, Dept Chem, Taegu 702701, South Korea

[5] Kyungpook Natl Univ, Dept Appl Chem, Taegu 702701, South Korea

[6] ETRI, IT BT Grp, Taejon 305700, South Korea

来源：

CURRENT APPLIED PHYSICS | 2009年 / 9卷

关键词：

MRI; T2 contrast agent; USPIO; PCLNP; RING-OPENING POLYMERIZATION;

D O I：

10.1016/j.cap.2008.08.039

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

A new synthetic method leading to the formation of polycaprolactone (PCL)/iron oxide nanoparticles using polyvinylpyrrolidone (PVP) is described. The unique feature of this method is that the conventional polymerization step can be avoided. A stable colloidal dispersion of the PCL-coated iron oxide nanoparticles (PCLNP) is thus formed in the presence of PVP as a stabilizer. The PCLNP has a mean diameter of 20-50 nm as measured by TEM. Magnetic measurement by SQUID shows that the PCLNP has a strong superparamagnetism to be used as a liver MR T2 agent. (C) 2008 Elsevier B.V. All rights reserved.

引用

页码：S19 / S21

页数：3

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