Antithrombotic effects of low-molecular-weight heparin calcium (LMWH-Ca) in experimental models

被引：6
|
作者：
Ji, H
Li, SP
Cheng, X
Cheng, HR
Ng, TB
Li, P
Li, NS
机构：
[1] China Pharmaceut Univ, Dept Pharmacol, Nanjing 210009, Peoples R China
[2] Chinese Univ Hong Kong, Dept Biochem, Hong Kong, Peoples R China
[3] Hefei Siu Fung USTC Pharmaceut Co Ltd, Hefei, Peoples R China
[4] China Pharmaceut Univ, Dept Pharmacognosy, Nanjing 210009, Peoples R China
来源：
GENERAL PHARMACOLOGY | 1999年 / 33卷 / 02期
关键词：
low-molecular-weight heparin; heparin; antithrombotic agent;
D O I：
10.1016/S0306-3623(98)00276-6
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
The antithrombotic activity of low-molecular-weight heparin calcium (LMWH-Ca) was studied in venous and arterial thrombosis models, arterial thrombosis model in rats, arterio-venous shunt model and venous thrombosis model. in rabbits. The data showed that LMWH-Ca reduced thrombus formation in a dose-dependent manner. It suggests that LMWH-Ca is a potent antithrombotic agent for venous thrombosis, and also may be a beneficial therapeutic agent in arterial thrombosis. (C) 1999 Elsevier Science Inc. All rights reserved.
引用
收藏
页码：207 / 211
页数：5
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