An Algorithm for Identifying and Classifying Cerebral Palsy in Young Children

被引:87
|
作者
Kuban, Karl C. K. [1 ]
Allred, Elizabeth N. [3 ,4 ]
O'Shea, Michael [2 ]
Paneth, Nigel [5 ]
Pagano, Marcello [4 ]
Leviton, Alan [3 ]
机构
[1] Boston Univ, Boston Med Ctr, Dept Pediat, Div Pediat Neurol, Boston, MA 02215 USA
[2] Wake Forest Univ, Dept Neonatol, Winston Salem, NC 27109 USA
[3] Harvard Univ, Childrens Hosp Boston, Dept Neurol, Neuroepidemiol Unit, Boston, MA USA
[4] Harvard Univ, Harvard Sch Publ Hlth, Dept Biostat, Boston, MA 02115 USA
[5] Michigan State Univ, Sparrow Med Ctr, E Lansing, MI 48824 USA
来源
JOURNAL OF PEDIATRICS | 2008年 / 153卷 / 04期
关键词
D O I
10.1016/j.jpeds.2008.04.013
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Objective To develop an algorithm on the basis of data obtained with a reliable, standardized neurological examination and report the prevalence of cerebral palsy (CP) subtypes (disparesis, hemiparesis, and quadriparesis) in a cohort of 2-year-old children born before 28 weeks gestation. Study design We compared children with CP subtypes on extent of handicap and frequency of microcephaly, cognitive impairment, and screening positive for autism. Results Of the 1056 children examined, 11.4% (120) were given an algorithm-based classification of CP. Of these children, 31% had disparesis. 17% had hemiparesis, and 52% had quadriparesis. Children with quadriparesis were 9 times more likely than children with diparesis (76% versus 8%) to be more highly impaired and 5 times more likely than children with diparesis to be microcephalic (43% versus 8%). They were more than twice as likely as children with diparesis to have a score <70 on the mental scale of the BSID-II (75% versus 34%) and had the highest rate of the Modified Checklist for Autism in Toddlers positivity (76%) compared with children with diparesis (30%) and children without CP (18%). Conclusion We developed an algorithm that Classifies CP subtypes. which Should permit comparison among studies. Extent of gross motor dysfunction and rates of co-morbidities are highest in children with quadriparesis and lowest in children with diparesis.
引用
收藏
页码:466 / 472
页数:7
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