G protein-coupled receptor kinase 2 can enhance beta-arrestin recruitment to the D2 dopamine receptor in the absence of receptor phosphorylation

被引:1
|
作者
Sanchez-Soto, Marta [1 ]
Schardien, Kayla [1 ]
Inbody, Laura [1 ]
Free, R. [1 ]
Sibley, David [1 ]
机构
[1] NINDS, NIH, Bethesda, MD 20892 USA
来源
FASEB JOURNAL | 2020年 / 34卷
关键词
D O I
10.1096/fasebj.2020.34.s1.03478
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
下载
收藏
页数:2
相关论文
共 50 条
  • [41] Conformational selection guides β-arrestin recruitment at a biased G protein-coupled receptor
    Kleist, Andrew B.
    Jenjak, Shawn
    Sente, Andrija
    Laskowski, Lauren J.
    Szpakowska, Martyna
    Calkins, Maggie M.
    Anderson, Emilie, I
    McNally, Lisa M.
    Heukers, Raimond
    Bobkov, Vladimir
    Peterson, Francis C.
    Thomas, Monica A.
    Chevigne, Andy
    Smit, Martine J.
    McCorvy, John D.
    Babu, M. Madan
    Volkman, Brian F.
    SCIENCE, 2022, 377 (6602) : 222 - +
  • [42] The D1 dopamine receptor is constitutively phosphorylated by G protein-coupled receptor kinase 4
    Rankin, ML
    Marinec, PS
    Cabrera, DM
    Wang, Z
    Jose, PA
    Sibley, DR
    MOLECULAR PHARMACOLOGY, 2006, 69 (03) : 759 - 769
  • [43] Phosphorylation-independent regulation of metabotropic glutamate receptor signaling by G protein-coupled receptor kinase 2
    Dhami, GK
    Anborgh, PH
    Dale, LB
    Sterne-Marr, R
    Ferguson, SSG
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (28) : 25266 - 25272
  • [44] Phosphorylation of phosducin and phosducin-like protein by G protein-coupled receptor kinase 2
    Ruiz-Gómez, A
    Humrich, J
    Murga, C
    Quitterer, U
    Lohse, MJ
    Mayor, F
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (38) : 29724 - 29730
  • [45] G Protein-coupled Receptor Kinase 4 (GRK4) Regulates the Phosphorylation and Function of the Dopamine D3 Receptor
    Villar, Van Anthony M.
    Jones, John E.
    Armando, Ines
    Palmes-Saloma, Cynthia
    Yu, Peiying
    Pascua, Annabelle M.
    Keever, Lindsay
    Arnaldo, Francis B.
    Wang, Zheng
    Luo, Yingjin
    Felder, Robin A.
    Jose, Pedro A.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2009, 284 (32) : 21425 - 21434
  • [46] Identification of G protein-coupled receptor kinase 2 phosphorylation sites responsible for agonist-stimulated δ-opioid receptor phosphorylation
    Guo, J
    Wu, YL
    Zhang, WB
    Zhao, J
    Devi, LA
    Pei, G
    Ma, L
    MOLECULAR PHARMACOLOGY, 2000, 58 (05) : 1050 - 1056
  • [47] G protein-coupled receptor kinase 2-mediated phosphorylation of ezrin is required for G protein-coupled receptor-dependent reorganization of the actin cytoskeleton
    Cant, SH
    Pitcher, JA
    MOLECULAR BIOLOGY OF THE CELL, 2005, 16 (07) : 3088 - 3099
  • [48] β2-adrenergic receptor stimulated, G protein-coupled receptor kinase 2 mediated, phosphorylation of ribosomal protein P2
    Freeman, JLR
    Gonzalo, P
    Pitcher, JA
    Claing, A
    Lavergne, JP
    Reboud, JP
    Lefkowitz, RJ
    BIOCHEMISTRY, 2002, 41 (42) : 12850 - 12857
  • [49] Peptide substrates for G protein-coupled receptor kinase 2
    Asai, Daisuke
    Toita, Riki
    Murata, Masaharu
    Katayama, Yoshiki
    Nakashima, Hideki
    Kang, Jeong-Hun
    FEBS LETTERS, 2014, 588 (13) : 2129 - 2132
  • [50] Clathrin box in G protein-coupled receptor kinase 2
    Shiina, T
    Arai, K
    Tanabe, S
    Yoshida, N
    Haga, T
    Nagao, T
    Kurose, H
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (35) : 33019 - 33026