The effect of entecavir on Hepatitis B virus-related cirrhosis

被引：0
|
作者：
Feng, Lei [1 ]
Chen, Yong-Jun [1 ]
Tang, Yi [1 ]
Xu, Jian-Yu [1 ]
Fan, Jing-Yun [1 ]
机构：
[1] Suining Cent Hosp, Digest Internal Med Dept, Suining, Sichuan Provinc, Peoples R China
来源：
PAKISTAN JOURNAL OF MEDICAL SCIENCES | 2012年 / 28卷 / 05期
关键词：
Entecavir; Hepatitis B virus; Cirrhosis; NAIVE PATIENTS; THERAPY; EFFICACY;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Objective: To explore the efficacy of Entecavir on hepatitis B virus-related decompensated cirrhosis. Methodology: One Hundred two cases of hepatitis B virus-related decompensated cirrhosis patients were randomly divided into treatment group (N=51) and control group (N=51). Both groups received conventional treatment, meanwhile treatment group received Entecavir for anti-virus treatment. Results: Comparison of liver function between the two groups was statistically significant (P < 0.01) at week 4, 8 and 12 after antiviral therapy, liver fibrosis contrast of two groups was statistically significant (P < 0.01) at week 4, 8 and 12 after antiviral therapy. Conclusions: Although Entecavir can be effective in treating hepatitis B virus-related decompensated cirrhosis, its resistance and course of treatment need to be further evaluated.
引用
收藏
页码：921 / 924
页数：4
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