Identification of Extended-Spectrum-β-Lactamase-Positive Klebsiella pneumoniae Urinary Tract Isolates Harboring KPC and CTX-M β-Lactamases in Nonhospitalized Patients

被引:10
|
作者
Kopacz, Joanna [1 ]
Mariano, Noriel [1 ]
Colon-Urban, Rita [4 ]
Sychangco, Paul [1 ]
Wehbeh, Wehbeh [1 ,2 ]
Segal-Maurer, Sorana [1 ,2 ]
Urban, Carl [1 ,3 ]
机构
[1] New York Hosp Queens, Dr James J Rahal Div Infect Dis, Flushing, NY USA
[2] Weill Cornell Med Coll, Dept Med, New York, NY USA
[3] New York Univ, Sch Med, Dept Microbiol, New York, NY USA
[4] SUNY Coll Old Westbury, Old Westbury, NY 11568 USA
关键词
ESCHERICHIA-COLI; MOLECULAR EPIDEMIOLOGY; HOSPITALIZED-PATIENTS; COMMUNITY; CARBAPENEMASE; INFECTIONS; RESIDENTS; AMERICA;
D O I
10.1128/AAC.00043-13
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Forty-seven extended-spectrum-beta-lactamase-positive Klebsiella pneumoniae urinary tract isolates from nonhospitalized patients were identified, and 79% harbored KPC and/or CTX-M beta-lactamases. Approximately 90% of the isolates were resistant to trimethoprim-sulfamethoxazole and levofloxacin, and 40% were resistant to a carbapenem, while 92% were susceptible to polymyxin B, 87% were susceptible to tigecycline, and 79% were susceptible to fosfomycin. Increased use of broader-spectrum antibiotics may help to prevent their dissemination and reduce the risk of progression to invasive disease.
引用
收藏
页码:5166 / 5169
页数:4
相关论文
共 50 条
  • [21] Emergence of CTX-M-15 extended-spectrum β-lactamase-producing Klebsiella pneumoniae isolates in Bosnia and Herzegovina
    Dedeic-Ljubovic, A.
    Hukic, M.
    Pfeifer, Y.
    Witte, W.
    Padilla, E.
    Lopez-Ramis, I.
    Alberti, S.
    CLINICAL MICROBIOLOGY AND INFECTION, 2010, 16 (02) : 152 - 156
  • [22] CTX-M Type Beta-Lactamase Frequency and Antibiotic Co-resistance in Extended Spectrum Beta-Lactamase Producing Klebsiella pneumoniae Strains
    Nazik, Hasan
    Ongen, Betigul
    Sarikaya, Aysel
    Kuvat, Nuray
    Ilktac, Mehmet
    TURKIYE KLINIKLERI TIP BILIMLERI DERGISI, 2011, 31 (02): : 300 - 306
  • [23] An outbreak of a CTX-M-type β-lactamase-producing Klebsiella pneumoniae:: the importance of using cefpodoxime to detect extended-spectrum β-lactamases
    Brenwald, NP
    Jevons, G
    Andrews, JM
    Xiong, JH
    Hawkey, PM
    Wise, R
    JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2003, 51 (01) : 195 - U24
  • [24] Incidence of extended-spectrum beta-lactamase-producing Klebsiella pneumoniae in patients with urinary tract infection
    Ghafourian, Sobhan
    Sekawi, Zamberi
    Neela, Vasanthakumari
    Khosravi, Afra
    Rahbar, Mohammad
    Sadeghifard, Nourkhoda
    SAO PAULO MEDICAL JOURNAL, 2012, 130 (01): : 37 - 43
  • [25] Distribution of Genotypes between CTX-M-Producing and Non-Extended-Spectrum-β-Lactamase-Producing Klebsiella pneumoniae Isolates
    Park, Yong Gyu
    Jo, Irene
    Park, Yeon-Joon
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2015, 59 (07) : 4362 - 4362
  • [26] Occurrence of AmpC chromosomally β-lactamase ACT-1 and extended spectrum β-lactamases type TEM, SHV and CTX-M in clinical isolates of Enterobacter cloacae
    Biendo, M.
    Manoliu, C.
    Canarelli, B.
    Thomas, D.
    Hamdad-Daoudi, F.
    Rousseau, F.
    Laurans, G.
    Eb, F.
    INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2007, 29 : S136 - S136
  • [27] Coproduction of 16S rRNA Methyltransferase RmtD or RmtG with KPC-2 and CTX-M Group Extended-Spectrum β-Lactamases in Klebsiella pneumoniae (vol 57, pg 2397, 2013)
    Bueno, Maria Fernanda C.
    Francisco, Gabriela R.
    O'Hara, Jessica A.
    Garcia, Doroti de Oliveira
    Doi, Yohei
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2016, 60 (01) : 714 - 714
  • [28] Occurrence and characteristics of extended-spectrum-β-lactamase- and pAmpC-producing Klebsiella pneumoniae isolated from companion animals with urinary tract infections
    Lee, Megan Min Yi
    Kuan, Nan-Ling
    Li, Zhi-Yi
    Yeh, Kuang-Sheng
    PLOS ONE, 2024, 19 (01):
  • [29] Livestock Manure as Potential Reservoir of CTX-M Type Extended-spectrum β-lactamase Producing Escherichia coli and Klebsiella pneumoniae Associated with Carbapenemase Production
    Devi, Leimapokpam Sumitra
    Broor, Shobha
    Chakravarti, Anita
    Chattopadhya, Debasish
    JOURNAL OF PURE AND APPLIED MICROBIOLOGY, 2020, 14 (01): : 171 - 181
  • [30] Extended-spectrum β-lactamases in Klebsiella pneumoniae bloodstream isolates from seven countries:: Dominance and widespread prevalence of SHV- and CTX-M-type β-lactamases
    Paterson, DL
    Hujer, KM
    Hujer, AM
    Yeiser, B
    Bonomo, MD
    Rice, LB
    Bonomo, RA
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2003, 47 (11) : 3554 - 3560