PROTEIN ENGINEERING Chemistry gets the assist

被引：1

作者：

Nestl, Bettina M. ^{[1
]}

Hauer, Bernhard ^{[1
]}

机构：

[1] Univ Stuttgart, Inst Tech Biochem, D-70174 Stuttgart, Germany

来源：

NATURE CHEMICAL BIOLOGY | 2013年 / 9卷 / 08期

关键词：

CYCLOPROPANE;

D O I：

10.1038/nchembio.1291

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Integration of chemistry-based approaches into enzyme engineering provides a versatile strategy for biocatalyst development with the potential for improved performance and new catalytic activities. Application of this strategy led to the development of a whole-cell catalyst capable of converting olefins into cyclopropanes, synthetic intermediates used in the synthesis of more functionalized cycloalkanes and acyclic compounds.

引用

页码：470 / 471

页数：2

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