A novel synthesis of 5-hydroxy-2,2-dimethyl-10-propyl-2H-pyrano[2,3-f]chromen-8-one

被引：19
|
作者：
Fox, ME
Lennon, IC
Meek, G
机构：
[1] Chirotech Technol Ltd, Cambridge CB4 0WG, England
[2] Sarawak MediChem Inc, Woodridge, IL USA
来源：
TETRAHEDRON LETTERS | 2002年 / 43卷 / 16期
关键词：
selective desulfonation; chromene synthesis; calanolide A;
D O I：
10.1016/S0040-4039(02)00428-8
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A concise synthesis of 5-hydroxy-2.2-dimethyl-10-propyl-2H-pyrano[2.3-f]chromen-8-one utilising a novel selective desulfonylation protocol is described. This method provides facile access to a key intermediate for the asymmetric synthesis of calanolide A. (C), 2002 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：2899 / 2902
页数：4
相关论文
共 50 条
  • [31] CONVENIENT SYNTHESIS OF 2,2-DIMETHYL-3,4-DIHYDRO-2H-PYRANO[2,3-B]QUINOLINES
    Parsekar, Sonia B.
    Amonkar, Chandan P.
    Parameswaran, Peruninakulath S.
    Tilve, Santosh G.
    SYNTHETIC COMMUNICATIONS, 2010, 40 (21) : 3251 - 3258
  • [32] One-Pot Synthesis of Alkyl 4-alkyl-2,8-dioxo-2H,8H-pyrano[2,3-f]chromene-10-carboxylates and Alkyl 2(E)-3-[(4-alkyl-2-oxo-2H-chromen-7-yl)oxy]acrylates
    Asghari, Sakineh
    Baharfar, Robabeh
    Mohammadian, Reza
    Darabi, Samaneh Ahangar
    LETTERS IN ORGANIC CHEMISTRY, 2015, 12 (01) : 50 - 54
  • [33] New entry to 9-acetyl/formyl-substituted 2H,8H-pyrano[2,3-f]chromen-2-ones through Baylis-Hillman reaction
    Raghotham, A.
    Lavanya, T.
    Reddy, P. Pratap
    SYNTHETIC COMMUNICATIONS, 2008, 38 (14) : 2459 - 2464
  • [34] A facile synthesis of 6-amino-2H, 4H-pyrano[2,3-F]pyrazole-5-carbonitriles in deep eutectic solvent
    Manisha R.Bhosle
    Lalit D.Khillare
    Sambhaji T.Dhumal
    Ramrao A.Mane
    Chinese Chemical Letters, 2016, 27 (03) : 370 - 374
  • [35] SYNTHESIS AND CLEAVAGE REACTIONS OF 9-ARYL-4H,8H-PYRANO[2,3-F](1,4)BENZOXAZIN-4-ONE DERIVATIVES
    SHANKER, MSS
    REDDY, RB
    MOULI, GVPC
    REDDY, YD
    JOURNAL OF THE INDIAN CHEMICAL SOCIETY, 1989, 66 (02) : 138 - 139
  • [36] Synthesis of pyrano[2,3-f]chromen-2,8-diones and pyrano[3,2-g]chromen-2,8-diones based on o-hydroxyformyl(acyl)neoflavonoids
    Moskvina, V. S.
    Khilya, V. P.
    CHEMISTRY OF NATURAL COMPOUNDS, 2008, 44 (01) : 16 - 23
  • [37] Synthesis of pyrano[2,3-f]chromen-2,8-diones and pyrano[3,2-g]chromen-2,8-diones based on o-hydroxyformyl(acyl)neoflavonoids
    V. S. Moskvina
    V. P. Khilya
    Chemistry of Natural Compounds, 2008, 44
  • [38] Synthesis and biological activity of meso-tetrakis (2,10-dioxo-2H, 10H-pyrano [2,3-f] chromene-9-yl) porphyrins
    Kumar, V. Naveen
    Reddy, Y. Thirupathi
    Narasimhareddy, P.
    Rajitha, B.
    De Clercq, E.
    ARKIVOC, 2006, : 181 - 188
  • [39] Microwave-assisted synthesis, molecular docking and antimicrobial activity of novel 2-(3-aryl,1-phenyl-1H-pyrazol-4-yl)-8H-pyrano[2,3-f]chromen-4-ones
    Ashok, Dongamanti
    Rangu, Kavitha
    Rao, Velagapuri Hanumantha
    Gundu, Srinivas
    Srilata, Ballu
    Vijjulatha, Manga
    MEDICINAL CHEMISTRY RESEARCH, 2016, 25 (03) : 501 - 514
  • [40] 1-(5-Hydroxy-7-methoxy-2,2-dimethyl-2H-chromen-6-yl)ethan-1-one
    Liu, Bingjing
    Chen, Guangying
    Cen, Changchun
    Song, Xinming
    Han, Changri
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2010, 66 : O1441 - U1688
12345