Cow's Milk Allergy, Asthma, and Pediatric IBD

被引：39
|
作者：
Virta, Lauri J. [1 ]
Ashorn, Merja [2 ]
Kolho, Kaija-Leena [3 ,4 ]
机构：
[1] Social Insurance Inst, Dept Res, Turku, Finland
[2] Univ Tampere, Pediat Res Ctr, FIN-33101 Tampere, Finland
[3] Univ Helsinki, Childrens Hosp, Cent Hosp, FIN-00029 Helsinki, Finland
[4] Univ Helsinki, FIN-00029 Helsinki, Finland
来源：
JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION | 2013年 / 56卷 / 06期
关键词：
children; Crohn disease; ulcerative colitis; INFLAMMATORY-BOWEL-DISEASE; RISK; INFANCY;
D O I：
10.1097/MPG.0b013e318285e9d8
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
We identified a total of 595 Finnish children born in 1994-2008 and diagnosed as having inflammatory bowel disease (IBD) by October 2010 from the National Reimbursement Register (based on certificates including the diagnostic criteria) to determine whether the presence of cow's milk allergy (CMA) or asthma is associated with the risk of contracting IBD (altogether 2380 matched controls). A diagnosis of CMA in infancy was associated with Crohn disease (odds ratio [OR] 1.92, confidence interval [CI] 1.09-3.36, P<0.05) and ulcerative colitis (OR 1.71, CI 1.04-2.83, P<0.05), but childhood asthma only with Crohn disease (OR 2.33, CI 1.41-3.86, P - 0.001). Thus, CMA in infants is a risk factor for contracting pediatric IBD and accordingly, asthma for Crohn disease.
引用
收藏
页码：649 / 651
页数：3
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