Blood eosinophil counts predict treatment response in patients with severe eosinophilic asthma

被引：49
|
作者：
Ortega, Hector [1 ]
Katz, Lynn [1 ]
Gunsoy, Necdet [2 ]
Keene, Oliver [2 ]
Yancey, Steven [1 ]
机构：
[1] GlaxoSmithKline, Resp Therapeut Area, Res Triangle Pk, NC 27709 USA
[2] GlaxoSmithKline, Clin Stat, Stockley Pk, England
来源：
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY | 2015年 / 136卷 / 03期
关键词：
MEPOLIZUMAB;
D O I：
10.1016/j.jaci.2015.05.039
中图分类号：
R392 [医学免疫学];
学科分类号：
100102 ;
摘要：
引用
收藏
页码：825 / +
页数：2
相关论文
共 50 条
  • [21] Blood eosinophil count group shifts and kinetics in severe eosinophilic asthma
    Lugogo, Njira L.
    Kreindler, James L.
    Martin, Ubaldo J.
    Cook, Bill
    Hirsch, Ian
    Trudo, Frank J.
    ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY, 2020, 125 (02) : 171 - 176
  • [22] Fractional Exhaled Nitric Oxide and the Peripheral Blood Eosinophil Count as Biomarkers of the Response to Mepolizumab in Patients with Severe Eosinophilic Asthma
    Shrimanker, R.
    Pavord, I. D.
    Price, R.
    Bradford, E. S.
    Keene, O. N.
    Yancey, S.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2018, 197
  • [23] Treatment Resistance in Severe Asthma Patients With a Combination of High Fraction of Exhaled Nitric Oxide and Low Blood Eosinophil Counts
    Hoshino, Yuki
    Soma, Tomoyuki
    Uchida, Yoshitaka
    Shiko, Yuki
    Nakagome, Kazuyuki
    Nagata, Makoto
    FRONTIERS IN PHARMACOLOGY, 2022, 13
  • [24] The Effects Of Systemic Corticosteroids On Blood Eosinophil Counts In Patients With Asthma
    Bell, C.
    Lafeuille, M. -H.
    Duh, M.
    Germain, G.
    Lejeune, D.
    Hahn, B.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2017, 195
  • [25] Blood eosinophil dose response to oral corticosteroids in a population of patients with severe asthma
    Austin, Daren
    Pouliquen, Isabelle
    Keene, Oliver
    Yancey, Steve
    EUROPEAN RESPIRATORY JOURNAL, 2016, 48
  • [26] Efficacy Of 100 Mg SC Mepolizumab For Severe Eosinophilic Asthma (SEA) Across Blood Eosinophil Counts: Meta-Analysis
    Yancey, Steven W.
    Albers, Frank
    Bratton, Daniel J.
    Bradford, Eric S.
    Kwon, Namhee
    Chanez, Pascal
    Licskai, Christopher
    Quirce, Santiago
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2019, 143 (02) : AB101 - AB101
  • [27] Biological function of eosinophil extracellular traps in patients with severe eosinophilic asthma
    Choi, Youngwoo
    Duy Le Pham
    Lee, Dong-Hyun
    Lee, So-Hee
    Kim, Seung-Hyun
    Park, Hae-Sim
    EXPERIMENTAL AND MOLECULAR MEDICINE, 2018, 50 : 1 - 8
  • [28] Biological function of eosinophil extracellular traps in patients with severe eosinophilic asthma
    Youngwoo Choi
    Duy Le Pham
    Dong-Hyun Lee
    So-Hee Lee
    Seung-Hyun Kim
    Hae-Sim Park
    Experimental & Molecular Medicine, 2018, 50 : 1 - 8
  • [29] Blood eosinophil counts rarely reflect airway eosinophilia in children with severe asthma
    Ullmann, N.
    Bossley, C. J.
    Fleming, L.
    Silvestri, M.
    Bush, A.
    Saglani, S.
    ALLERGY, 2013, 68 (03) : 402 - 406
  • [30] Treatment response with mepolizumab in severe eosinophilic asthma patients with previous omalizumab treatment
    Magnan, A.
    Bourdin, A.
    Prazma, C. M.
    Albers, F. C.
    Price, R. G.
    Yancey, S. W.
    Ortega, H.
    ALLERGY, 2016, 71 (09) : 1335 - 1344
12345