Pathogenicity of an unusual highly virulent Marek's disease virus isolated in the United Kingdom

被引：0
|
作者：
Venugopal, K
Bland, AP
Ross, LJN
Payne, LN
机构：
来源：
CURRENT RESEARCH ON MAREK'S DISEASE | 1996年
关键词：
in situ hybridisation; Marek's disease; Meq transcript; strain C12/130;
D O I：
暂无
中图分类号：
S8 [畜牧、 动物医学、狩猎、蚕、蜂];
学科分类号：
0905 ;
摘要：
A highly virulent strain of Marek's disease virus, designated C12/130, was isolated in 1991 from a field outbreak in HVT vaccinated broiler breeders in the UK. The pathogenicity of the disease induced by this virus was studied in genetically susceptible and resistant specific-pathogen-free chickens. The virus induced severe early cytolytic disease causing mortality up to 25% in the first 2 weeks with marked lasting atrophic changes of the thymus and bursa of Fabricius. Severity of the disease varied between different lines and expression of the meg gene was detected by in situ hybridization in the infected tissues.
引用
收藏
页码：119 / 124
页数：6
相关论文
共 50 条
  • [41] Invasion of avian macrothages by highly virulent Marek's disease virus strain C12/130 represents a "tropic shift"in the pathogenesis
    Barrow, AD
    Burgess, SC
    Howes, K
    Venugopal, K
    CURRENT PROGRESS ON MAREK'S DISEASE RESEARCH, 2001, : 63 - 67
  • [42] Expression of interferon gamma by a highly virulent strain of Newcastle disease virus decreases its pathogenicity in chickens
    Susta, Leonardo
    Cornax, Ingrid
    Diel, Diego G.
    Garcia, Stivalis Cardenas
    Miller, Patti J.
    Liu, Xiufan
    Hu, Shunlin
    Brown, Corrie C.
    Afonso, Claudio L.
    MICROBIAL PATHOGENESIS, 2013, 61-62 : 73 - 83
  • [43] A comprehensive screen for chicken proteins that interact with proteins unique to virulent strains of Marek's disease virus
    Niikura, M
    Liu, HC
    Dodgson, JB
    Cheng, HH
    POULTRY SCIENCE, 2004, 83 (07) : 1117 - 1123
  • [44] Marek's disease virus latency
    Morgan, RW
    Xie, Q
    Cantello, JL
    Miles, AM
    Bernberg, EL
    Kent, J
    Anderson, A
    MAREK'S DISEASE, 2001, 255 : 223 - 243
  • [45] Genomics and Marek's disease virus
    Burnside, J.
    Morgan, R. W.
    CYTOGENETIC AND GENOME RESEARCH, 2007, 117 (1-4) : 376 - 387
  • [46] Emergence and Pathogenicity of Highly Virulent Cryptococcus gattii Genotypes in the Northwest United States
    Byrnes, Edmond J., III
    Li, Wenjun
    Lewit, Yonathan
    Ma, Hansong
    Voelz, Kerstin
    Ren, Ping
    Carter, Dee A.
    Chaturvedi, Vishnu
    Bildfell, Robert J.
    May, Robin C.
    Heitman, Joseph
    PLOS PATHOGENS, 2010, 6 (04) : 1 - 16
  • [47] Biological characterization and pathogenicity of a newly isolated Chinese highly virulent genotype GIIa porcine epidemic diarrhea virus strain
    Liping Zhang
    Xinsheng Liu
    Qiaoling Zhang
    Peng Zhou
    Yuzhen Fang
    Zhaoliang Dong
    Donghong Zhao
    Weiyan Li
    Jiaxin Feng
    Yongguang Zhang
    Yonglu Wang
    Archives of Virology, 2019, 164 : 1287 - 1295
  • [48] Biological characterization and pathogenicity of a newly isolated Chinese highly virulent genotype GIIa porcine epidemic diarrhea virus strain
    Zhang, Liping
    Liu, Xinsheng
    Zhang, Qiaoling
    Zhou, Peng
    Fang, Yuzhen
    Dong, Zhaoliang
    Zhao, Donghong
    Li, Weiyan
    Feng, Jiaxin
    Zhang, Yongguang
    Wang, Yonglu
    ARCHIVES OF VIROLOGY, 2019, 164 (05) : 1287 - 1295
  • [49] Isolation and pathogenicity of a highly virulent group III porcine Getah virus in China
    Wu, Yu
    Gao, Xiaopeng
    Kuang, Zhanpeng
    Lin, Limiao
    Zhang, Hao
    Yin, Lijuan
    Hong, Jiabing
    Ren, Bohua
    Li, Qunhui
    Wang, Lianxiang
    FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 2024, 14
  • [50] Molecular characterization and phylogenetic analysis of a virulent Marek's disease virus field strain in broiler chickens in Japan
    Abd-Ellatieff, Hoda A.
    Abou Rawash, Abdelrahman A.
    Ellakany, Hany F.
    Goda, Wael M.
    Suzuki, T.
    Yanai, Tokuma
    AVIAN PATHOLOGY, 2018, 47 (01) : 47 - 57
12345