A novel synthetic route to fused propenochlorin and benzochlorin photodynamic therapy probes

被引：8
|
作者：
Li, GL
Mehta, R
Srikrishnan, T
Nurco, DJ
Tabaczynski, WA
Alderfer, JL
Smith, KM
Dougherty, TJ
Pandey, RK [1 ]
机构：
[1] Roswell Pk Canc Inst, PDT Ctr, Div Chem, Buffalo, NY 14263 USA
[2] Univ Calif Davis, Dept Chem, Davis, CA 95616 USA
来源：
CHEMICAL COMMUNICATIONS | 2002年 / 11期
关键词：
D O I：
10.1039/b202280j
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Reaction of meso-(2-formylvinyl) octaethylporphyrin with (CH3)(3)SiCN-Cu(OTf)(2) produced unexpected 10(3)-trimethyl-siloxyl and 10(3)-hydroxyl fused propenochlorins which, in H2SO4, underwent subsequent migration of the 8-ethyl group to the 10(3)-position of the exocyclic benzene ring to form a novel benzochlorin.
引用
收藏
页码：1172 / 1173
页数：2
相关论文
共 50 条
  • [31] A GENERAL SYNTHETIC ROUTE TO FUSED FURANS - TOTAL SYNTHESIS OF (+)-PALLESCENSIN-A
    SHISHIDO, K
    UMIMOTO, K
    OUCHI, M
    IRIE, O
    OMODANI, T
    TAKATA, T
    SHIBUYA, M
    JOURNAL OF CHEMICAL RESEARCH-S, 1993, (02): : 58 - 59
  • [32] A novel synthetic route for the preparation of hydrolytically degradable synthetic hydrogels
    Cho, Eunhee
    Kutty, Jaishankar K.
    Datar, Kedar
    Lee, Jeoung Soo
    Vyavahare, Naren R.
    Webb, Ken
    JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 2009, 90A (04) : 1073 - 1082
  • [33] Novel Cyanoarylporphyrazines with Triazole Groups at the Macrocycle Periphery as Potential Sensibilizers of Photodynamic Therapy and Optical Probes of Intracellular Viscosity
    Lermontova, S. A.
    Grigoryev, I. S.
    Peskova, N. N.
    Balalaeva, I. V.
    Boyarskii, V. P.
    Klapshina, L. G.
    RUSSIAN JOURNAL OF GENERAL CHEMISTRY, 2018, 88 (11) : 2339 - 2346
  • [34] Synthetic efforts towards a selective photodynamic therapy agent
    Venable, Frances A.
    Best, Quinn
    Scott, Colleen
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2012, 243
  • [35] Targeting of the tumor microcirculation by photodynamic therapy with a synthetic porphycene
    Abels, C
    Szeimies, RM
    Steinbach, P
    Richert, C
    Goetz, AE
    JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, 1997, 40 (03) : 305 - 312
  • [36] Novel Cyanoarylporphyrazines with Triazole Groups at the Macrocycle Periphery as Potential Sensibilizers of Photodynamic Therapy and Optical Probes of Intracellular Viscosity
    S. A. Lermontova
    I. S. Grigoryev
    N. N. Peskova
    I. V. Balalaeva
    V. P. Boyarskii
    L. G. Klapshina
    Russian Journal of General Chemistry, 2018, 88 : 2339 - 2346
  • [37] New stable synthetic bacteriochlorins for photodynamic therapy of melanoma
    Mroz, Pawel
    Huang, Ying-Ying
    Janjua, Sahar
    Zhiyentayev, Timur
    Ruzie, Christian
    Borbas, K. Eszter
    Fan, Dazhong
    Krayer, Michael
    Balasubramanian, Thiagarajan
    Yang, Eun Kyung
    Kee, Hooi Ling
    Holten, Dewey
    Lindsey, Jonathan S.
    Hamblin, Michael R.
    12TH WORLD CONGRESS OF THE INTERNATIONAL PHOTODYNAMIC ASSOCIATION: PHOTODYNAMIC THERAPY: BACK TO THE FUTURE, 2009, 7380
  • [38] Novel porphyrin derivatives for photodynamic therapy
    Hayes, Timothy
    White, Tyler
    Scarbrough, Megan
    Bradshaw, Joseph
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2017, 253
  • [39] A Novel synthetic route to tantalum carbide.
    Chan, J
    Kauzlarich, SM
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1996, 211 : 282 - INOR
  • [40] Novel synthetic route to dl-grandisol.
    Goldblum, AA
    Bartlett, WR
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2002, 223 : B218 - B218
12345