Anti-leukemia activity of human gamma delta T cells

被引：5
|
作者：
Siegers, Gabrielle M. [1 ,2 ]
机构：
[1] Univ Western Ontario, Robarts Res Inst, Imaging Res Labs, London, ON, Canada
[2] Univ Toronto, Princess Margaret Hosp, Cell Therapy Program, Toronto, ON, Canada
来源：
ONCOIMMUNOLOGY | 2012年 / 1卷 / 02期
关键词：
gamma delta T cells; expansion protocol; preclinical investigation; in vivo bioluminescent xenograft model; adoptive cellular immunotherapy; PERIPHERAL-BLOOD; LYMPHOCYTES; LEUKEMIA;
D O I：
10.4161/onci.1.2.18231
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Two recently published articles from Siegers and colleagues detail both a novel human gamma delta T cell (GDTc) expansion protocol and a bioluminescent xenograft model of Ph+ leukemia, in which GDTc adoptive therapy was tested. Additionally, B-cell chronic lymphocytic leukemia-derived cells were newly identified as targets of preferentially expanded Vdelta1 GDTc.
引用
收藏
页码：237 / 239
页数：3
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