Umbilical cord-derived mesenchymal stem cells in neurodegenerative disorders: from literature to clinical practice

被引：41
|
作者：
Reyhani, Samira [1 ]
Abbaspanah, Bahareh [2 ]
Mousavi, Seyed Hadi [3 ]
机构：
[1] Univ Tehran Med Sci, Sch Allied Med Sci, Dept Lab Sci, Tehran 1417744361, Iran
[2] Royan Stem Cell Technol Co, Cord Blood Bank, Tehran 1417744361, Iran
[3] Univ Tehran Med Sci, Sch Allied Med Sci, Dept Hematol, Tehran 1417744361, Iran
来源：
REGENERATIVE MEDICINE | 2020年 / 15卷 / 04期
关键词：
Alzheimer's disease; amyotrophic lateral sclerosis; cerebral palsy; Huntington disease; multiple sclerosis; neurodegenerative disease; Parkinson's disease; spinal cord injury; stem cell therapies; umbilical cord mesenchymal stem cells; AMYOTROPHIC-LATERAL-SCLEROSIS; STROMAL CELLS; PARKINSONS-DISEASE; RAT MODEL; FUNCTIONAL RECOVERY; DOPAMINERGIC CELLS; MOUSE MODEL; IN-VITRO; TRANSPLANTATION; INJURY;
D O I：
10.2217/rme-2019-0119
中图分类号：
Q813 [细胞工程];
学科分类号：
摘要：
Mesenchymal stem cells (MSCs) have provided a promising tool for cell therapy. Umbilical cord (UC) is one of the best sources of MSCs since its collection is noninvasive, and effortless, and the cells from this source are more capable and prolific. It has been proven that the differentiation, migration and protective properties of UC-MSCs are superior compared with other kinds of stem cells. Moreover, incurable neurodegenerative diseases, such as Alzheimer's disease, multiple sclerosis, Parkinson's disease and Huntington, encourage scientists to apply UC-MSCs transplantation in order to find a definite treatment. This review will focus on the preclinical and clinical use of mesenchymal stem cells derived from human umbilical cord in the treatment of neurodegenerative disorders.
引用
收藏
页码：1561 / 1578
页数：18
相关论文
共 50 条
  • [21] Human Umbilical Cord-Derived Mesenchymal Stem Cells for Acute Respiratory Distress Syndrome
    Yip, Hon-Kan
    Fang, Wen-Feng
    Li, Yi-Chen
    Lee, Fan-Yen
    Lee, Chen-Hsiang
    Pei, Sung-Nan
    Ma, Ming-Chun
    Chen, Kuan-Hung
    Sung, Pei-Hsun
    Lee, Mel S.
    CRITICAL CARE MEDICINE, 2020, 48 (05) : E391 - E399
  • [22] Umbilical cord-derived mesenchymal stem cells: Strategies, challenges, and potential for cutaneous regeneration
    Yang S.
    Huang S.
    Feng C.
    Fu X.
    Frontiers of Medicine, 2012, 6 (1) : 41 - 47
  • [23] Effects of hypoxic culture conditions on umbilical cord-derived human mesenchymal stem cells
    Antonina Lavrentieva
    Ingrida Majore
    Cornelia Kasper
    Ralf Hass
    Cell Communication and Signaling, 8
  • [24] Influence of obstetric factors on osteogenic potential of umbilical cord-derived mesenchymal stem cells
    Letizia Penolazzi
    Renata Vecchiatini
    Stefania Bignardi
    Elisabetta Lambertini
    Elena Torreggiani
    Alessandro Canella
    Tiziana Franceschetti
    Giorgio Calura
    Fortunato Vesce
    Roberta Piva
    Reproductive Biology and Endocrinology, 7
  • [25] Reduction of Emphysema Severity by Human Umbilical Cord-Derived Mesenchymal Stem Cells in Mice
    Laiman, Vincent
    Lee, Yueh-Lun
    Hou, Yu-Wei
    Fang, Yu-Ting
    Chen, You-Yin
    Lo, Yu-Chun
    Heriyanto, Didik Setyo
    Lan, Shu-Chi
    Chen, Chia-Ling
    Chen, Xiao-Yue
    Lee, Kang-Yun
    Chang, Jer-Hwa
    Chuang, Hsiao-Chi
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 23 (16)
  • [26] Effects of hypoxic culture conditions on umbilical cord-derived human mesenchymal stem cells
    Lavrentieva, Antonina
    Majore, Ingrida
    Kasper, Cornelia
    Hass, Ralf
    CELL COMMUNICATION AND SIGNALING, 2010, 8
  • [27] The Effects of Indoxyl Sulfate on Human Umbilical Cord-Derived Mesenchymal Stem Cells In Vitro
    Wang, Wei
    Liu, Xueyong
    Wang, Wei
    Li, Jinghua
    Li, Yuanyuan
    Li, Liping
    Wang, Shaohua
    Zhang, Jianchun
    Zhang, Youkang
    Huang, Haichang
    CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 2016, 38 (01) : 401 - 414
  • [28] Interferon-γ alters the microRNA profile of umbilical cord-derived mesenchymal stem cells
    Chi, Ying
    Cui, Junjie
    Wang, Youwei
    Du, Wenjing
    Chen, Fang
    Li, Zongjin
    Ma, Fengxia
    Song, Baoquan
    Xu, Fangyun
    Zhao, Qingjun
    Han, Zhibo
    Han, Zhongchao
    MOLECULAR MEDICINE REPORTS, 2016, 14 (05) : 4187 - 4197
  • [29] Platelet lysate induces chondrogenic differentiation of umbilical cord-derived mesenchymal stem cells
    Ghmkin Hassan
    Mohammad Bahjat
    Issam Kasem
    Chadi Soukkarieh
    Majd Aljamali
    Cellular & Molecular Biology Letters, 2018, 23
  • [30] Impact of administering umbilical cord-derived mesenchymal stem cells to cynomolgus monkeys with endometriosis
    Tsuji, Shunichiro
    Mukai, Takeo
    Tsuchiya, Hideaki
    Iwatani, Chizuru
    Nakamura, Akiko
    Nagamura-Inoue, Tokiko
    Murakami, Takashi
    REPRODUCTIVE MEDICINE AND BIOLOGY, 2023, 22 (01)
12345