Paraneoplastic cerebellar degeneration in a patient with ovarian cancer

被引：6

作者：

Chien, Hung-Ju ^{[1
,2
]}

Lee, Chuo-Yu ^{[2
,3
]}

Chen, Lu-An ^{[2
,3
]}

Wu, Chao-Chih ^{[4
]}

Chang, Chih-Long ^{[1
,2
,4
,5
]}

机构：

[1] Mackay Mem Hosp, Dept Obstet & Gynecol, Taipei 10449, Taiwan

[2] Mackay Med Coll, Taipei, Taiwan

[3] Mackay Mem Hosp, Dept Neurol, Taipei 10449, Taiwan

[4] Mackay Mem Hosp, Dept Med Res, Taipei 10449, Taiwan

[5] Mackay Med Coll, Dept Med, New Taipei City, Taiwan

来源：

TAIWANESE JOURNAL OF OBSTETRICS & GYNECOLOGY | 2015年 / 54卷 / 03期

关键词：

anti-Yo antibody; paraneoplastic cerebellar degeneration; ovarian cancer;

D O I：

10.1016/j.tjog.2014.03.012

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Objective: Herein, we report a case of ovarian serous carcinoma with paraneoplastic cerebellar degeneration. Case report: A 44-year-old female presented to our hospital with dizziness, slurred speech, and ataxic gait. Brain magnetic resonance imaging was normal. A lumbar puncture revealed a normal cell count in the cerebrospinal fluid, but slightly elevated protein. Her serum cancer antigen -125 level was high (2126.4 U/mL), and abdominal computed tomography disclosed a pelvic mass measuring 11 cm in diameter. Exploratory laparotomy was then performed, and a frozen section of the tumor revealed serous carcinoma. Conclusion: According to the surgical findings and pathological report, The International Federation of Gynecology and Obstetrics (FIGO) Stage IIIC, Grade 3, serous-type ovarian cancer was diagnosed. Due to the abovementioned symptoms and signs, we performed a serial test to document the presence of anti-Yo antibody in this patient. Copyright (C) 2015, Taiwan Association of Obstetrics & Gynecology. Published by Elsevier Taiwan LLC. All rights reserved.

引用

页码：313 / 315

页数：3

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