Dkk1 mediated inhibition of Wnt Signaling in postnatal mice leads to loss of TEC progenitors and thymic degeneration

被引：0
|
作者：
Pezzano, Mark [1 ]
Osada, Masako [1 ]
Jardine, Logan [1 ]
Misir, Ruth [1 ]
Andl, Thomas [2 ]
Millar, Sarah [3 ]
机构：
[1] CUNY City Coll, Biol, New York, NY USA
[2] Vanderbilt Univ, Ctr Med, Nashville, TN 37232 USA
[3] Univ Penn, Philadelphia, PA 19104 USA
来源：
JOURNAL OF IMMUNOLOGY | 2010年 / 184卷
关键词：
D O I：
暂无
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
36.32
引用
收藏
页数：1
相关论文
共 27 条
  • [21] Mesp1 Mediates Cardiovascular Differentiation By Dkk-1 Driven Inhibition Of Wnt-signaling And Is A Suitable Tool For Isolation Of Es Cell Derived Cardiovascular Progenitors
    David, Robert
    CIRCULATION, 2008, 118 (18) : S491 - S491
  • [22] Baicalin induced colon cancer cells apoptosis through miR-217/DKK1-mediated inhibition of Wnt signaling pathway
    Yanmei Jia
    Lirong Chen
    Songjia Guo
    Yuanhong Li
    Molecular Biology Reports, 2019, 46 : 1693 - 1700
  • [23] Baicalin induced colon cancer cells apoptosis through miR-217/DKK1-mediated inhibition of Wnt signaling pathway
    Jia, Yanmei
    Chen, Lirong
    Guo, Songjia
    Li, Yuanhong
    MOLECULAR BIOLOGY REPORTS, 2019, 46 (02) : 1693 - 1700
  • [24] Structure-based mutation analysis shows the importance of LRP5 β-propeller 1 in modulating Dkk1-mediated inhibition of Wnt signaling
    Bhat, Bheem M.
    Allen, Kristina M.
    Liu, Wei
    Graham, James
    Morales, Art
    Anisowicz, Anthony
    Lam, Ho-Sun
    McCauley, Catherine
    Coleburn, Valerie
    Cain, Michael
    Fortier, Eric
    Bhat, Ramesh A.
    Bex, Frederick J.
    Yaworsky, Paul J.
    GENE, 2007, 391 (1-2) : 103 - 112
  • [25] Reduced affinity to and inhibition by DKK1 form a common mechanism by which high bone mass-associated missense mutations in LRP5 affect canonical Wnt signaling
    Ai, M
    Holmen, SL
    Van Hul, W
    Williams, BO
    Warman, ML
    MOLECULAR AND CELLULAR BIOLOGY, 2005, 25 (12) : 4946 - 4955
  • [26] Novel LRP5 missense mutation in a patient with a high bone mass phenotype results in decreased DKK1-mediated inhibition of Wnt signaling
    Balemans, Wendy
    Devogelaer, Jean-Pierre
    Cleiren, Erna
    Piters, Elke
    Caussin, Emanuelle
    Van Hul, Wim
    JOURNAL OF BONE AND MINERAL RESEARCH, 2007, 22 (05) : 708 - 716
  • [27] Loss of BMP signaling mediated by BMPR1A in osteoblasts leads to differential bone phenotypes in mice depending on anatomical location of the bones
    Zhang, Honghao
    Zhang, Yanshuai
    Terajima, Masahiko
    Romanowicz, Genevieve
    Liu, Yangjia
    Omi, Maiko
    Bigelow, Erin
    Joiner, Danese M.
    Waldorff, Erik, I
    Zhu, Peizhi
    Raghavan, Mekhala
    Lynch, Michelle
    Kamiya, Nobuhiro
    Zhang, Rongqing
    Jepsen, Karl J.
    Goldstein, Steve
    Morris, Michael D.
    Yamauchi, Mitsuo
    Kohn, David H.
    Mishina, Yuji
    BONE, 2020, 137
123