Background Fractional technology overcomes the problems of ablative lasers, such as inaccurate depth control and damage to the epidermis. Minimally invasive fractional radiofrequency microneedle devices allow for more-selective heating of the dermis. Objective To evaluate the clinical efficacy of fractional radiofrequency microneedle (ERM) treatment in acne scars and large facial pores. Materials and Methods Thirty patients with acne scars and large facial pores were enrolled. Bipolar radiofrequency energy was delivered to the skin through the electrodes of the FRM device. Skin lesions were evaluated according to grade of acne scars, Investigator Global Assessment of large pores, skin surface roughness, transepidermal water loss (TEWL), dermal density, microscopic and composite image, sebum measurement, and questionnaires regarding patient satisfaction. Results The grade of acne scars and Investigator Global Assessment of large pores improved in more than 70% of all patients. Skin surface roughness, dermal density, and microscopic and composite images also improved, whereas TEWL and sebum measurement did not change. Conclusion Clinical improvement from FRM treatment appeared to be related to dermal matrix regeneration. FRM treatment may be effective in improving acne scars and facial pores.
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Army Med Univ, Southwest Hosp, Dept Dermatol, Chongqing 400038, Peoples R China
Luxury Skinctr, Dept Cosmet Dermatol, Xian 710048, Peoples R ChinaArmy Med Univ, Southwest Hosp, Dept Dermatol, Chongqing 400038, Peoples R China
Lan, Ting
Tang, Li
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Army Med Univ, Southwest Hosp, Dept Dermatol, Chongqing 400038, Peoples R ChinaArmy Med Univ, Southwest Hosp, Dept Dermatol, Chongqing 400038, Peoples R China
Tang, Li
Xia, Aiai
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Army Med Univ, Southwest Hosp, Dept Dermatol, Chongqing 400038, Peoples R ChinaArmy Med Univ, Southwest Hosp, Dept Dermatol, Chongqing 400038, Peoples R China
Xia, Aiai
Hamblin, Michael R.
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Massachusetts Gen Hosp, Wellman Ctr Photomed, Boston, MA 02114 USA
Harvard Med Sch, Dept Dermatol, Boston, MA 02115 USA
Univ Johannesburg, Laser Res Ctr, Fac Hlth Sci, ZA-2028 Doornfontein, South AfricaArmy Med Univ, Southwest Hosp, Dept Dermatol, Chongqing 400038, Peoples R China
Hamblin, Michael R.
Jian, Dan
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Cent South Univ, Xiangya Hosp, Dept Dermatol, Changsha 410008, Hunan, Peoples R ChinaArmy Med Univ, Southwest Hosp, Dept Dermatol, Chongqing 400038, Peoples R China
Jian, Dan
Yin, Rui
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Army Med Univ, Southwest Hosp, Dept Dermatol, Chongqing 400038, Peoples R ChinaArmy Med Univ, Southwest Hosp, Dept Dermatol, Chongqing 400038, Peoples R China