Background Fractional technology overcomes the problems of ablative lasers, such as inaccurate depth control and damage to the epidermis. Minimally invasive fractional radiofrequency microneedle devices allow for more-selective heating of the dermis. Objective To evaluate the clinical efficacy of fractional radiofrequency microneedle (ERM) treatment in acne scars and large facial pores. Materials and Methods Thirty patients with acne scars and large facial pores were enrolled. Bipolar radiofrequency energy was delivered to the skin through the electrodes of the FRM device. Skin lesions were evaluated according to grade of acne scars, Investigator Global Assessment of large pores, skin surface roughness, transepidermal water loss (TEWL), dermal density, microscopic and composite image, sebum measurement, and questionnaires regarding patient satisfaction. Results The grade of acne scars and Investigator Global Assessment of large pores improved in more than 70% of all patients. Skin surface roughness, dermal density, and microscopic and composite images also improved, whereas TEWL and sebum measurement did not change. Conclusion Clinical improvement from FRM treatment appeared to be related to dermal matrix regeneration. FRM treatment may be effective in improving acne scars and facial pores.
机构:
Louis Dermatol Clin, Gyeonggi Do, South KoreaUniv Ulsan, Coll Med, Dept Dermatol, Asan Med Ctr, Seoul 138736, South Korea
Lee, Hae Woong
Kim, Jae Kyung
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Univ Ulsan, Coll Med, Dept Dermatol, Asan Med Ctr, Seoul 138736, South KoreaUniv Ulsan, Coll Med, Dept Dermatol, Asan Med Ctr, Seoul 138736, South Korea
Kim, Jae Kyung
Moon, Seong Hun
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Hanyang Univ, Dept Dermatol, Hanyang Univ Hosp, Coll Med, Seoul 133791, South KoreaUniv Ulsan, Coll Med, Dept Dermatol, Asan Med Ctr, Seoul 138736, South Korea
Moon, Seong Hun
Ko, Joo Yeon
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Hanyang Univ, Dept Dermatol, Hanyang Univ Hosp, Coll Med, Seoul 133791, South KoreaUniv Ulsan, Coll Med, Dept Dermatol, Asan Med Ctr, Seoul 138736, South Korea
Ko, Joo Yeon
Lee, Mi Woo
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Univ Ulsan, Coll Med, Dept Dermatol, Asan Med Ctr, Seoul 138736, South KoreaUniv Ulsan, Coll Med, Dept Dermatol, Asan Med Ctr, Seoul 138736, South Korea
Lee, Mi Woo
Chang, Sung Eun
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Univ Ulsan, Coll Med, Dept Dermatol, Asan Med Ctr, Seoul 138736, South KoreaUniv Ulsan, Coll Med, Dept Dermatol, Asan Med Ctr, Seoul 138736, South Korea
机构:
CHA Univ, Dept Dermatol, CHA Bundang Med Ctr, 59 Yatap Ro, Songnam 463712, South KoreaCHA Univ, Dept Dermatol, CHA Bundang Med Ctr, 59 Yatap Ro, Songnam 463712, South Korea
Park, Jae Yang
Lee, Eo Gin
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CHA Univ, Dept Dermatol, CHA Bundang Med Ctr, 59 Yatap Ro, Songnam 463712, South KoreaCHA Univ, Dept Dermatol, CHA Bundang Med Ctr, 59 Yatap Ro, Songnam 463712, South Korea
Lee, Eo Gin
Yoon, Moon Soo
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CHA Univ, Dept Dermatol, CHA Bundang Med Ctr, 59 Yatap Ro, Songnam 463712, South KoreaCHA Univ, Dept Dermatol, CHA Bundang Med Ctr, 59 Yatap Ro, Songnam 463712, South Korea
Yoon, Moon Soo
Lee, Hee Jung
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CHA Univ, Dept Dermatol, CHA Bundang Med Ctr, 59 Yatap Ro, Songnam 463712, South KoreaCHA Univ, Dept Dermatol, CHA Bundang Med Ctr, 59 Yatap Ro, Songnam 463712, South Korea
机构:
Anhui Med Univ, Affiliated Hosp 1, Dept Dermatol, Hefei, Peoples R China
Anhui Med Univ, Key Lab Dermatol, Minist Educ, Hefei, Peoples R China
Inflammat & Immune Mediated Dis Lab Anhui Prov, Hefei, Peoples R ChinaAnhui Med Univ, Affiliated Hosp 1, Dept Dermatol, Hefei, Peoples R China
Lyu, Jiajie
Jiang, Liyong
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Anhui Med Univ, Affiliated Hosp 1, Dept Dermatol, Hefei, Peoples R ChinaAnhui Med Univ, Affiliated Hosp 1, Dept Dermatol, Hefei, Peoples R China
Jiang, Liyong
Tang, Mingjun
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Anhui Med Univ, Affiliated Hosp 1, Dept Dermatol, Hefei, Peoples R ChinaAnhui Med Univ, Affiliated Hosp 1, Dept Dermatol, Hefei, Peoples R China
Tang, Mingjun
Zheng, Liyun
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Anhui Med Univ, Affiliated Hosp 1, Dept Dermatol, Hefei, Peoples R China
Anhui Med Univ, Key Lab Dermatol, Minist Educ, Hefei, Peoples R China
Inflammat & Immune Mediated Dis Lab Anhui Prov, Hefei, Peoples R ChinaAnhui Med Univ, Affiliated Hosp 1, Dept Dermatol, Hefei, Peoples R China
Zheng, Liyun
Liu, Shengxiu
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Anhui Med Univ, Affiliated Hosp 1, Dept Dermatol, Hefei, Peoples R China
Anhui Med Univ, Key Lab Dermatol, Minist Educ, Hefei, Peoples R China
Inflammat & Immune Mediated Dis Lab Anhui Prov, Hefei, Peoples R ChinaAnhui Med Univ, Affiliated Hosp 1, Dept Dermatol, Hefei, Peoples R China
机构:
Nanjing Med Univ, Dept Dermatol, Affiliated Hosp 1, Nanjing, Peoples R China
Dr Zhous Cosmet Dermatol Clin, Dept Cosmet Dermatol, Nanjing, Peoples R ChinaNanjing Med Univ, Dept Dermatol, Affiliated Hosp 1, Nanjing, Peoples R China
Ding, Ziwei
Guo, Yuan
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Dr Zhous Cosmet Dermatol Clin, Dept Cosmet Dermatol, Nanjing, Peoples R ChinaNanjing Med Univ, Dept Dermatol, Affiliated Hosp 1, Nanjing, Peoples R China
Guo, Yuan
Guo, Yuehong
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Dr Zhous Cosmet Dermatol Clin, Dept Cosmet Dermatol, Nanjing, Peoples R ChinaNanjing Med Univ, Dept Dermatol, Affiliated Hosp 1, Nanjing, Peoples R China
Guo, Yuehong
Tang, Yanqiu
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Nanjing Med Univ, Dept Dermatol, Affiliated Hosp 1, Nanjing, Peoples R ChinaNanjing Med Univ, Dept Dermatol, Affiliated Hosp 1, Nanjing, Peoples R China
Tang, Yanqiu
Yin, Xufeng
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Nanjing Med Univ, Dept Dermatol, Affiliated Hosp 1, Nanjing, Peoples R ChinaNanjing Med Univ, Dept Dermatol, Affiliated Hosp 1, Nanjing, Peoples R China
Yin, Xufeng
Hua, Hui
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Nantong Univ, Dept Dermatol, Nantong Peoples Hosp 3, Nantong, Peoples R ChinaNanjing Med Univ, Dept Dermatol, Affiliated Hosp 1, Nanjing, Peoples R China
Hua, Hui
Zhou, Zhanchao
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Dr Zhous Cosmet Dermatol Clin, Dept Cosmet Dermatol, Nanjing, Peoples R ChinaNanjing Med Univ, Dept Dermatol, Affiliated Hosp 1, Nanjing, Peoples R China
Zhou, Zhanchao
Zhou, Bingrong
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Nanjing Med Univ, Dept Dermatol, Affiliated Hosp 1, Nanjing, Peoples R ChinaNanjing Med Univ, Dept Dermatol, Affiliated Hosp 1, Nanjing, Peoples R China