Is there a relationship between prostate volume and Gleason score?

被引:6
|
作者
Mir, Maria Carmen [1 ]
Planas, Jacques [1 ]
Raventos, Carles Xavier [1 ]
de Torres, Ines Maria [2 ]
Trilla, Enrique [1 ]
Cecchini, Lluis [1 ]
Orsola, Anna [1 ]
Morote, Juan [1 ]
机构
[1] Univ Autonoma Barcelona, Sch Med, Vall Hebron Hosp, Dept Urol, E-08193 Barcelona, Spain
[2] Univ Autonoma Barcelona, Sch Med, Vall Hebron Hosp, Dept Pathol Anat, E-08193 Barcelona, Spain
关键词
prostate neoplasia; biopsy; high grade; Gleason score;
D O I
10.1111/j.1464-410X.2008.07696.x
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
To review the relationship between the Gleason grade and prostate volume in biopsy and radical prostatectomy (RP) specimens, and thus assess the hypothesis that smaller prostates have a greater incidence of high-grade tumours. We selected 390 patients who had RP at our institution, with a prostate-specific antigen (PSA) level of < 10 ng/mL and who had not had hormonal therapy. We retrospectively reviewed the data for transrectal ultrasonography (TRUS)-guided prostate biopsies from these patients and the RP specimens. Indications for biopsy included a PSA level of >= 4 ng/mL or an abnormal digital rectal examination. High-grade tumours were defined as having a Gleason score of >= 7. The TRUS volume was statistically related to the rate of high-grade tumours at biopsy and RP. On multivariate analyses, TRUS volume was a significant predictor of high-grade tumour for biopsy and RP specimens, with an inverse relationship between high-grade tumours and prostate volume for biopsy and RP specimens. Our data suggest that there is a relationship between the rate of high-grade tumours and prostate volume even in biopsy and RP specimens and it is not an artefact related to the biopsy.
引用
收藏
页码:563 / 565
页数:3
相关论文
共 50 条
  • [31] Trends in Gleason score for prostate cancer diagnosed between 1983 and 1993
    Gilliland, FD
    Gleason, DF
    Hunt, WC
    Stone, N
    Harlan, LC
    Key, CR
    JOURNAL OF UROLOGY, 2001, 165 (03): : 846 - 850
  • [32] Gleason Score and Laterality Concordance between Prostate Biopsy and Prostatectomy Specimens
    Nepple, Kenneth G.
    Wahls, Terry L.
    Hillis, Stephen L.
    Joudi, Fadi N.
    INTERNATIONAL BRAZ J UROL, 2009, 35 (05): : 559 - 564
  • [33] Gleason Score Correlation Between Prostate Biopsy and Radical Prostatectomy Specimens
    Ozturk, Erdem
    Yikilmaz, Taha Numan
    UROONKOLOJI BULTENI-BULLETIN OF UROONCOLOGY, 2018, 17 (01): : 1 - 4
  • [34] THE WEIGHTED GLEASON SCORE OF PROSTATE BIOPSY SPECIMENS IMPROVES THE PREDICTION OF PATHOLOGIC GLEASON SCORE
    Cho, Eric
    Kaplan, Joshua
    Harbin, Andrew
    Kamenko, Anastasiya
    Ramsey, Frederick
    Mydlo, Jack
    Eun, Daniel
    Reese, Adam
    JOURNAL OF UROLOGY, 2016, 195 (04): : E244 - E244
  • [35] GLOBAL GLEASON SCORE ON PROSTATE NEEDLE BIOPSIES IS THE BEST PREDICTOR OF PROSTATECTOMY GLEASON SCORE
    Shevchuk, Maria
    Mudaliar, Kumaran
    El Douaihy, Youssef
    Peters, David
    Srivastava, Abhishek
    Grover, Sonal
    John, Majnu
    Leung, Robert
    Tewari, Ashutosh
    JOURNAL OF UROLOGY, 2010, 183 (04): : E791 - E791
  • [36] Underestimation of Gleason score at prostate biopsy reflects sampling error in lower volume tumours
    Corcoran, Niall M.
    Hovens, Chris M.
    Hong, Matthew K. H.
    Pedersen, John
    Casey, Rowan G.
    Connolly, Stephen
    Peters, Justin
    Harewood, Laurence
    Gleave, Martin E.
    Goldenberg, S. Larry
    Costello, Anthony J.
    BJU INTERNATIONAL, 2012, 109 (05) : 660 - 664
  • [37] Prediction of Final Gleason Score in Radical Prostatectomy Utilizing Global Gleason Score, Highest Gleason Score and Largest Volume Gleason Score Parameters in Needle Core Biopsies
    Feroze, Asra
    Rivera, Julia
    Liu, Yu
    Wang, Haibo
    Bhalla, Ritu
    LABORATORY INVESTIGATION, 2024, 104 (03) : S945 - S946
  • [38] Is the preoperative urinary prostate cancer gene 3 (PCA3) score's associated with Gleason score dependent tumor volume and Gleason pattern specific tumor volume?
    Auprich, M.
    Chun, F. K. H.
    Mayrhofer, K.
    Haese, A.
    Mannweiler, S.
    Ward, J. F.
    Gutschi, S. T.
    Babaian, R.
    Pummer, K.
    Augustin, H.
    EUROPEAN UROLOGY SUPPLEMENTS, 2012, 11 (01) : E1004 - U103
  • [39] IS THE PREOPERATIVE URINARY PROSTATE CANCER GENE 3 (PCA3) SCORE'S ASSOCIATED WITH GLEASON SCORE DEPENDENT TUMOUR VOLUME AND GLEASON PATTERN SPECIFIC TUMOUR VOLUME?
    Auprich, Marco
    Mannweiler, Sebastian
    Chun, Felix K. H.
    Mayrhofer, Katrin
    Haese, Alexander
    Ward, John F.
    Babaian, Richard
    Pummer, Karl
    Augustin, Herbert
    JOURNAL OF UROLOGY, 2012, 187 (04): : E900 - E900
  • [40] The Relationship Between Prostate-Specific Antigen and TNM Classification or Gleason Score in Prostate Cancer Patients With Low Prostate-Specific Antigen Levels
    Izumi, Kouji
    Ikeda, Hiroko
    Maolake, Aerken
    Machioka, Kazuaki
    Nohara, Takahiro
    Narimoto, Kazutaka
    Ueno, Satoru
    Kadono, Yoshifumi
    Kitagawa, Yasuhide
    Konaka, Hiroyuki
    Mizokami, Atsushi
    Namiki, Mikio
    PROSTATE, 2015, 75 (10): : 1034 - 1042