Efficient three-component synthesis of 5-(6-hydroxy-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-5,12-dihydrobenzo[b] pyrimido[5,4-g][1,8] naphthyridine-2,4(1H,3H)-dione

被引：1
|
作者：
Ebrahimlo, Ali Reza Molla [1 ]
机构：
[1] Islamic Azad Univ, Dept Chem, Khoy Branch, Khoy, Iran
来源：
HETEROCYCLIC COMMUNICATIONS | 2018年 / 24卷 / 02期
关键词：
barbituric acid; benzo[b][1,8]naphthyridine; 2-chloro-3-formylquinoline; 1,8-NAPHTHYRIDINES; DERIVATIVES; AGENTS; DNA;
D O I：
10.1515/hc-2017-0265
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
1,8-Naphthyridine derivatives are important heterocyclic compounds. A facile and efficient one-pot procedure for the synthesis of 5-(6-hydroxy-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-5,12-dihydrobenzo[b]pyrimido[5,4-g][1,8]naphthyridine-2,4(1H,3H)-dione(3) via a three-component reaction of barbituric acid, 2-chloro-3-formylquinoline and ammonia under basic conditions is described.
引用
收藏
页码：75 / 77
页数：3
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