Efficient three-component synthesis of 5-(6-hydroxy-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-5,12-dihydrobenzo[b] pyrimido[5,4-g][1,8] naphthyridine-2,4(1H,3H)-dione

被引：1

作者：

Ebrahimlo, Ali Reza Molla ^{[1
]}

机构：

[1] Islamic Azad Univ, Dept Chem, Khoy Branch, Khoy, Iran

来源：

HETEROCYCLIC COMMUNICATIONS | 2018年 / 24卷 / 02期

关键词：

barbituric acid; benzo[b][1,8]naphthyridine; 2-chloro-3-formylquinoline; 1,8-NAPHTHYRIDINES; DERIVATIVES; AGENTS; DNA;

D O I：

10.1515/hc-2017-0265

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

1,8-Naphthyridine derivatives are important heterocyclic compounds. A facile and efficient one-pot procedure for the synthesis of 5-(6-hydroxy-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-5,12-dihydrobenzo[b]pyrimido[5,4-g][1,8]naphthyridine-2,4(1H,3H)-dione(3) via a three-component reaction of barbituric acid, 2-chloro-3-formylquinoline and ammonia under basic conditions is described.

引用

页码：75 / 77

页数：3

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