Regulation of Metabolism: A Cross Talk Between Gut Microbiota and Its Human Host

被引：38
|
作者：
Burcelin, Remy [1 ]
机构：
[1] Fac Med Toulouse, INSERM, Inst Malad Metabol & Cardiovasc, F-31073 Toulouse, France
来源：
PHYSIOLOGY | 2012年 / 27卷 / 05期
关键词：
HIGH-FAT-DIET; INSULIN-RESISTANCE; INTESTINAL MICROBIOTA; INDUCED OBESITY; ADIPOSE-TISSUE; T-CELLS; INFLAMMATION; MICE; ENDOTOXEMIA; MECHANISMS;
D O I：
10.1152/physiol.00023.2012
中图分类号：
Q4 [生理学];
学科分类号：
071003 ;
摘要：
The recent epidemic of obesity and diabetes and the diversity at the individual level could be explained by the intestinal microbiota-to-host relationship. More than four million gene products from the microbiome could interact with the immune system to induce a tissue metabolic infection, which is the molecular origin of the low-grade inflammation that characterizes the onset of obesity and diabetes.
引用
收藏
页码：300 / 307
页数：8
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