Bioactivity of sol-gel derived organically modified silicates .1. In vitro examination

被引：122

作者：

Tsuru, K ^{[1
]}

Ohtsuki, C ^{[1
]}

Osaka, A ^{[1
]}

Iwamoto, T ^{[1
]}

Mackenzie, JD ^{[1
]}

机构：

[1] UNIV CALIF LOS ANGELES,SCH ENGN & APPL SCI,DEPT MAT,LOS ANGELES,CA 90024

来源：

JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE | 1997年 / 8卷 / 03期

关键词：

D O I：

10.1023/A:1018523203667

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Bioactivity was investigated for several organically modified silicates (Ormosils) prepared through sol-gel processes. Ca(II)-free samples were biocompatible only, but Ca(II)containing samples were bioactive and deposited apatite during immersion in a simulated body fluid. The ease of silanol (Si-OH) group formation on the ormosils was considered a predominant factor controlling the bioactivity, while the effect of dissolved Ca(II) ions to increase the degree of supersaturation in the simulated body fluid is secondary.

引用

页码：157 / 161

页数：5

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