Bioactivity of sol-gel derived organically modified silicates .1. In vitro examination

被引：122
|
作者：
Tsuru, K [1 ]
Ohtsuki, C [1 ]
Osaka, A [1 ]
Iwamoto, T [1 ]
Mackenzie, JD [1 ]
机构：
[1] UNIV CALIF LOS ANGELES,SCH ENGN & APPL SCI,DEPT MAT,LOS ANGELES,CA 90024
来源：
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE | 1997年 / 8卷 / 03期
关键词：
D O I：
10.1023/A:1018523203667
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
Bioactivity was investigated for several organically modified silicates (Ormosils) prepared through sol-gel processes. Ca(II)-free samples were biocompatible only, but Ca(II)containing samples were bioactive and deposited apatite during immersion in a simulated body fluid. The ease of silanol (Si-OH) group formation on the ormosils was considered a predominant factor controlling the bioactivity, while the effect of dissolved Ca(II) ions to increase the degree of supersaturation in the simulated body fluid is secondary.
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收藏
页码：157 / 161
页数：5
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