Polycyclic N-Heterocyclic Compounds, Part 72: Reaction of N-([1]Benzofuro (or Benzothieno)[3,2-d]pyrimidin-4-yl)formamidine and N-(Pyrido[2,3-d]pyrimidin-4-yl)formamidine Derivatives with Hydroxylamine Hydrochloride

被引：1

作者：

Okuda, Kensuke ^{[1
]}

Tsuchie, Kiyoko ^{[2
]}

Hirota, Takashi ^{[2
]}

机构：

[1] Gifu Pharmaceut Univ, Lab Med & Pharmaceut Chem, Gifu 5011196, Japan

[2] Okayama Univ, Fac Pharmaceut Sci, Lab Pharmaceut Chem, Kita Ku, Okayama 7008530, Japan

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 2012年 / 49卷 / 04期

关键词：

AMIDE OXIME DERIVATIVES; N-(QUINAZOLIN-4-YL)AMIDINE DERIVATIVES;

D O I：

10.1002/jhet.850

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reactions of N-([1]benzofuro[3,2-d]pyrimidin-4-yl)formamidines with hydroxylamine hydrochloride gave rearranged cyclization products via ring cleavage of the pyrimidine component accompanied by a ring closure of the 1,2,4-oxadiazole to give N-[2-([1,2,4]oxadiazol-5-yl)[1]benzofuran-3-yl)formamide oximes. N-([1]Benzothieno[3,2-d]pyrimidin-4-yl)formamidines and N-(pyrido[2,3-d]pyrimidin-4-yl)formamidines with hydroxylamine hydrochloride gave similar results.

引用

页码：755 / 762

页数：8

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