Toward rational design of species-specific inhibitors of Pneumocystis carinii thymidylate synthase and Toxoplasma gondii dihydrofolate reductase-thymidylate synthase

被引：0
|
作者：
Peaslee, KAW [1 ]
Anderson, AC [1 ]
机构：
[1] Dartmouth Coll, Dept Chem, Burke Labs, Hanover, NH 03755 USA
来源：
JOURNAL OF EUKARYOTIC MICROBIOLOGY | 2001年
关键词：
D O I：
暂无
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
引用
收藏
页码：174S / 175S
页数：2
相关论文
共 50 条
  • [21] Analysis of the Plasmodium vivax dihydrofolate reductase-thymidylate synthase gene sequence
    de Pécoulas, PE
    Basco, LK
    Tahar, R
    Ouatas, T
    Mazabraud, A
    GENE, 1998, 211 (01) : 177 - 185
  • [22] Kaurane-Type Diterpenoids as Potential Inhibitors of Dihydrofolate Reductase-Thymidylate Synthase in New World Leishmania Species
    Herrera-Acevedo, Chonny
    de Menezes, Renata Priscila Barros
    de Sousa, Natalia Ferreira
    Scotti, Luciana
    Scotti, Marcus Tullius
    Coy-Barrera, Ericsson
    ANTIBIOTICS-BASEL, 2023, 12 (04):
  • [23] Combined gene deletion of dihydrofolate reductase-thymidylate synthase and pteridine reductase in Leishmania infantum
    Bhattacharya, Arijit
    Leprohon, Philippe
    Ouellette, Marc
    PLOS NEGLECTED TROPICAL DISEASES, 2021, 15 (04):
  • [24] Insights into the role of the junctional region of Plasmodium falciparum dihydrofolate reductase-thymidylate synthase
    Chaianantakul, Natpasit
    Sirawaraporn, Rachada
    Sirawaraporn, Worachart
    MALARIA JOURNAL, 2013, 12
  • [25] Cloning and heterologous expression of Plasmodium ovale dihydrofolate reductase-thymidylate synthase gene
    Tirakarn, Srisuda
    Riangrungroj, Pinpunya
    Kongsaeree, Palangpon
    Imwong, Mallika
    Yuthavong, Yongyuth
    Leartsakulpanich, Ubolsree
    PARASITOLOGY INTERNATIONAL, 2012, 61 (02) : 324 - 332
  • [26] Physical mapping across the dihydrofolate reductase-thymidylate synthase chromosome of Leishmania major
    Tosi, LRO
    Casagrande, L
    Beverley, SM
    Cruz, AK
    PARASITOLOGY, 1997, 114 : 521 - 529
  • [27] Predicting and harnessing protein flexibility in the design of species-specific inhibitors of thymidylate synthase
    Fritz, TA
    Tondi, D
    Finer-Moore, JS
    Costi, MP
    Stroud, RM
    CHEMISTRY & BIOLOGY, 2001, 8 (10): : 981 - 995
  • [28] Insights into the role of the junctional region of Plasmodium falciparum dihydrofolate reductase-thymidylate synthase
    Natpasit Chaianantakul
    Rachada Sirawaraporn
    Worachart Sirawaraporn
    Malaria Journal, 12
  • [29] PRODUCTION OF HETERO-DIMERIC DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE BIFUNCTIONAL ENZYME
    IWAKURA, M
    KOKUBU, T
    JOURNAL OF BIOCHEMISTRY, 1995, 118 (01): : 67 - 74
  • [30] Functional expression of the dihydrofolate reductase domain of Leishmania major dihydrofolate reductase-thymidylate synthase bifunctional protein
    Yu, PL
    Zhao, J
    Yu, M
    Reid, R
    Santi, DV
    PROTEIN EXPRESSION AND PURIFICATION, 1996, 8 (01) : 23 - 27
12345