Preclinical characterization of a novel STING agonist, MK-1454

被引：0

作者：

Cemerski, Saso ^{[1
]}

Altman, Michael ^{[1
]}

Bandi, Madhavi ^{[1
]}

Chang, Wonsuk ^{[2
]}

Chen, Yiping ^{[1
]}

Cui, Long ^{[1
]}

Cumming, Jared ^{[1
]}

Dorosh, Lauren ^{[1
]}

Flateland, Lauren ^{[1
]}

Ma, Yanhong ^{[1
]}

Javaid, Sarah ^{[1
]}

Ho, Thu ^{[3
]}

Kopinja, Johnny ^{[1
]}

Laskey, Jason ^{[1
]}

Minnihan, Ellen ^{[1
]}

Price, Laura ^{[3
]}

Mogg, Robin ^{[3
]}

O'Donnell, Gregory ^{[3
]}

Pan, Bo-Sheng ^{[1
]}

Perera, Samanthi ^{[1
]}

Piesvaux, Jennifer ^{[1
]}

Presland, Jeremy ^{[1
]}

Rakhilina, Larissa ^{[1
]}

Schroeder, Gottfried ^{[1
]}

Slavonic, Michael ^{[1
]}

Smock, Steven ^{[1
]}

Trotter, Benjamin Wesley ^{[1
]}

Wyss, Daniel ^{[2
]}

Zhao, Qing ^{[4
]}

Zhao, Shuxia ^{[1
]}

Sadekova, Svetlana ^{[5
]}

Yu, Ying ^{[5
]}

Khilnani, Anuradha ^{[4
]}

Tse, Archie ^{[4
]}

机构：

[1] Merck Res Labs, Boston, MA USA

[2] Merck Res Labs, Kenilworth, NJ USA

[3] Merck Res Labs, West Point, PA USA

[4] Merck Res Labs, Rahway, NJ USA

[5] Merck Res Labs, Palo Alto, CA USA

来源：

JOURNAL FOR IMMUNOTHERAPY OF CANCER | 2017年 / 5卷

关键词：

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

O31

引用

页数：2

共 50 条

[21] TAK-676: A Novel Stimulator of Interferon Genes (STING) Agonist Promoting Durable IFN-dependent Antitumor Immunity in Preclinical Studies
Cunniff, Elizabeth Carideo
Sato, Yosuke
Mai, Doanh
Appleman, Vicky A.
Iwasaki, Shinji
Kolev, Vihren
Matsuda, Atsushi
Shi, Judy
Mochizuki, Michiyo
Yoshikawa, Masato
Huang, Jian
Shen, Luhua
Haridas, Satyajeet
Shinde, Vaishali
Gemski, Chris
Roberts, Emily R.
Ghasemi, Omid
Bazzazi, Hojjat
Menon, Saurabh
Traore, Tary
Shi, Pu
Thelen, Tennille D.
Conlon, Joseph
Abu-Yousif, Adnan O.
Arendt, Christopher
Shaw, Michael H.
Okaniwa, Masanori
CANCER RESEARCH COMMUNICATIONS, 2022, 2 (06): : 489 - 502
[22] A novel STING agonist with systemic and durable anti-tumour activity
Wang, Xiyuan
Shen, Ancheng
Zhang, Yan
Chen, Xiaoxu
Ding, Jian
Zhang, Ao
Geng, Meiyu
Ding, Chunyong
Xie, Zuoquan
CLINICAL AND TRANSLATIONAL DISCOVERY, 2023, 3 (05):
[23] Initial preclinical development of a novel dual orexin receptor agonist
Silvani, Alessandro
Berteotti, Chiara
Bastianini, Stefano
Lo Martire, Viviana
Alvente, Sara
Matteoli, Gabriele
Ciani, Elisabetta
Trazzi, Stefania
Medici, Giorgio
Plazzi, Giuseppe
Zoccoli, Giovanna
JOURNAL OF SLEEP RESEARCH, 2024, 33
[24] Immune checkpoint inhibition improves antimyeloma activity of bortezomib and STING agonist combination in Vk*MYC preclinical model
Sokolowska, Olga
Rodziewicz-Lurzynska, Anna
Pilch, Zofia
Kedzierska, Hanna
Chlebowska-Tuz, Justyna
Sosnowska, Anna
Szumera-Cieckiewicz, Anna
Sokol, Kamil
Barankiewicz, Joanna
Salomon-Perzynski, Aleksander
Ciepiela, Olga
Lech-Maranda, Ewa
Golab, Jakub
Nowis, Dominika
CLINICAL AND EXPERIMENTAL MEDICINE, 2023, 23 (05) : 1563 - 1572
[25] MK-801, NOVEL GLUTAMATE ANTAGONIST AND NEUROPROTECTIVE AGENT - PRECLINICAL DATA
STAHL, S
EPILEPSIA, 1987, 28 (04) : 448 - 449
[26] Immune checkpoint inhibition improves antimyeloma activity of bortezomib and STING agonist combination in Vk*MYC preclinical model
Olga Sokolowska
Anna Rodziewicz-Lurzynska
Zofia Pilch
Hanna Kedzierska
Justyna Chlebowska-Tuz
Anna Sosnowska
Anna Szumera-Cieckiewicz
Kamil Sokol
Joanna Barankiewicz
Aleksander Salomon-Perzynski
Olga Ciepiela
Ewa Lech-Maranda
Jakub Golab
Dominika Nowis
Clinical and Experimental Medicine, 2023, 23 : 1563 - 1572
[27] Intratumoral or Subcutaneous MK-2118, a Noncyclic Dinucleotide STING Agonist, with or without Pembrolizumab, for Advanced or Metastatic Solid Tumors or Lymphomas
Luke, Jason J.
Sweis, Randy F.
Hecht, J. Randolph
Schneider, Reva
Stein, Mark N.
Golan, Talia
Yap, Timothy A.
Khilnani, Anuradha
Huang, Mo
Zhao, Runchen
Jemielita, Thomas
Patel, Sandip Pravin
CLINICAL CANCER RESEARCH, 2025, 31 (07) : 1233 - 1242
[28] Mechanistic insights into the antitumor activity of SB 11285-a novel STING agonist.
Zhou, Shenghua
Challa, Sreerupa
Nair, Vishal
Meher, Geeta
Sheri, Anjaneyulu
Gimi, Rayomand
Padmanabhan, Seetharamaiyer
Cleary, Dillon
Suppiah, Leena
Schmidt, Diane
Khedkar, Santosh
Iyer, Radhakrishnan
CANCER IMMUNOLOGY RESEARCH, 2020, 8 (04) : 124 - 125
[29] A novel STING agonist for cancer immunotherapy and a SARS-CoV-2 vaccine adjuvant
Wu, Jun-Jun
Zhao, Lang
Han, Bei-Bei
Hu, Hong-Guo
Zhang, Bo-Dou
Li, Wen-Hao
Chen, Yong-Xiang
Li, Yan-Mei
CHEMICAL COMMUNICATIONS, 2021, 57 (04) : 504 - 507
[30] 18F-FDG PET Visualizes Systemic STING Agonist-Induced Lymphocyte Activation in Preclinical Models
Le, Thuc M.
Lee, Hailey R.
Abt, Evan R.
Rashid, Khalid
Creech, Amanda L.
Liang, Keke
Cui, Jing
Cho, Arthur
Wei, Liu
Labora, Amanda
Chan, Charlotte
Sanchez, Eric
Kriti, Kriti
Karin, Daniel
Li, Luyi
Wu, Nanping
Mona, Christine
Carlucci, Giuseppe
Hugo, Willy
Wu, Ting-Ting
Donahue, Timothy R.
Czernin, Johannes
Radu, Caius G.
JOURNAL OF NUCLEAR MEDICINE, 2023, 64 (01) : 117 - 123

← 1 2 3 4 5 →