Relapsed acute lymphoblastic leukemia with unusual multiple bone invasions: A case report

被引：9
|
作者：
Hangai, Mayumi [1 ]
Watanabe, Kentaro [1 ]
Shiozawa, Ryosuke [1 ]
Hiwatari, Mitsuteru [1 ]
Ida, Kohmei [1 ]
Takita, Junko [1 ]
机构：
[1] Tokyo Univ Hosp, Dept Pediat, Tokyo 1138655, Japan
来源：
ONCOLOGY LETTERS | 2014年 / 7卷 / 04期
关键词：
computed tomography; positron emission tomography; acute lymphoblastic leukemia; bone relapse; RECURRENT MULTIFOCAL OSTEOMYELITIS; MARROW;
D O I：
10.3892/ol.2014.1820
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
The present study describes a unique pediatric case with multiple bone invasions of acute lymphoblastic leukemia (ALL) during remission. An eight-year-old male with a history of ALL was admitted complaining of intermittent and migrating pain in the limb 2 years following complete remission. Magnetic resonance imaging and whole-body positron emission tomography with F-18-fluorodeoxyglucose revealed abnormal multifocal involvement in the bones and corresponding soft tissues. Repeated bone marrow (BM) aspiration indicated normal cellular marrow without leukemic cells, and marked leukemic cell infiltration in different sections of the ilium, respectively. These findings suggested isolated bone relapse, and it is probable that systematic BM relapse occurred as a consequence.
引用
收藏
页码：991 / 993
页数：3
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