The UCSC Genome Browser database: 2019 update

被引:526
|
作者
Haeussler, Maximilian [1 ]
Zweig, Ann S. [1 ]
Tyner, Cath [1 ]
Speir, Matthew L. [1 ]
Rosenbloom, Kate R. [1 ]
Raney, Brian J. [1 ]
Lee, Christopher M. [1 ]
Lee, Brian T. [1 ]
Hinrichs, Angie S. [1 ]
Gonzalez, Jairo Navarro [1 ]
Gibson, David [1 ]
Diekhans, Mark [1 ]
Clawson, Hiram [1 ]
Casper, Jonathan [1 ]
Barber, Galt P. [1 ]
Haussler, David [1 ,2 ]
Kuhn, Robert M. [1 ]
Kent, W. James [1 ]
机构
[1] Univ Calif Santa Cruz, Genom Inst, Santa Cruz, CA 95064 USA
[2] Univ Calif Santa Cruz, Howard Hughes Med Inst, Santa Cruz, CA 95064 USA
关键词
INTEGRATIVE ANALYSIS; ENCODE DATA; ANNOTATION;
D O I
10.1093/nar/gky1095
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The UCSC Genome Browser (https://genome.ucsc.edu) is a graphical viewer for exploring genome annotations. For almost two decades, the Browser has provided visualization tools for genetics and molecular biology and continues to add new data and features. This year, we added a new tool that lets users interactively arrange existing graphing tracks into new groups. Other software additions include new formats for chromosome interactions, a ChIP-Seq peak display for track hubs and improved support for HGVS. On the annotation side, we have added gnomAD, TCGA expression, RefSeq Functional elements, GTEx eQTLs, CRISPR Guides, SNPpedia and created a 30-way primate alignment on the human genome. Nine assemblies now have RefSeq-mapped gene models.
引用
收藏
页码:D853 / D858
页数:6
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