Total synthesis of (+)-β-himachalene

被引：10

作者：

Ho, TL ^{[1
]}

Chein, RJ ^{[1
]}

机构：

[1] Natl Chiao Tung Univ, Dept Appl Chem, Hsinchu, Taiwan

来源：

HELVETICA CHIMICA ACTA | 2006年 / 89卷 / 02期

关键词：

D O I：

10.1002/hlca.200690025

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An enantioselective synthesis of (+)-beta-himachalene (2) was accomplished starting from (1S,2R)-1,2-epoxy-p-menth-8-ene (3) in 15 or 16 steps with an overall yield of ca. 6% (Schemes 3, 5, and 6). Key transformations include an Ireland Claisen rearrangement, a Corey oxidative cyclization, and a ring expansion.

引用

页码：231 / 239

页数：9

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