Tankyrase inhibition represses Wnt signaling and lung cancer growth

被引：0
|
作者：
Busch, Alexander M. [1 ]
Johnson, Kevin C. [1 ]
Tacchelly, Ofelia [1 ]
Wang, Zhenghan [1 ]
Ahmed, Yashi F. [1 ]
Dmitrovsky, Ethan [1 ]
Freemantle, Sarah J. [1 ]
机构：
[1] Dartmouth Coll, Hitchcock Med Ctr, Dartmouth Med Sch, Hanover, NH 03756 USA
来源：
CANCER RESEARCH | 2012年 / 72卷
关键词：
D O I：
10.1158/1538-7445.AM2012-973
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
973
引用
收藏
页数：1
相关论文
共 50 条
  • [1] Targeting WNT signaling in vivovia Tankyrase inhibition
    Schatoff, Emma M.
    Leach, Benjamin I.
    Foronda, Miguel
    Zafra, Maria Paz
    Goswami, Sukanya
    Dow, Lukas E.
    CANCER RESEARCH, 2018, 78 (13)
  • [2] Targeting WNT signaling in vivo via Tankyrase inhibition.
    Schatoff, Emma M.
    Leach, Benjamin I.
    Foronda, Miguel
    Zafra, Maria Paz
    Dow, Lukas
    CANCER RESEARCH, 2018, 78 (10) : 70 - 70
  • [3] Tankyrase and the Canonical Wnt Pathway Protect Lung Cancer Cells from EGFR Inhibition
    Casas-Selves, Matias
    Kim, Jihye
    Zhang, Zhiyong
    Helfrich, Barbara A.
    Gao, Dexiang
    Porter, Christopher C.
    Scarborough, Hannah A.
    Bunn, Paul A., Jr.
    Chan, Daniel C.
    Tan, Aik Choon
    DeGregori, James
    CANCER RESEARCH, 2012, 72 (16) : 4154 - 4164
  • [4] Wnt signaling in lung cancer
    Mazieres, J
    He, B
    You, L
    Xu, ZD
    Jablons, DA
    CANCER LETTERS, 2005, 222 (01) : 1 - 10
  • [5] Structural Basis and Selectivity of Tankyrase Inhibition by a Wnt Signaling Inhibitor WIKI4
    Haikarainen, Teemu
    Venkannagari, Harikanth
    Narwal, Mohit
    Obaji, Ezeogo
    Lee, Hao-Wei
    Nkizinkiko, Yves
    Lehtio, Lari
    PLOS ONE, 2013, 8 (06):
  • [6] Phospholipase Cγ1 represses colorectal cancer growth by inhibiting the Wnt/β-catenin signaling axis
    Shin, Kyeong Jin
    Jang, Hyun-Jun
    Lee, Yu Jin
    Lee, Yu Geon
    Suh, Pann-Ghill
    Yang, Yong Ryoul
    Chae, Young Chan
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2021, 577 : 103 - 109
  • [7] Inhibition of Growth of Esophageal Cancer by Alantolactone via Wnt/β-Catenin Signaling
    Wang, Zijie
    Hu, Qing
    Chen, Huan
    Shi, Lei
    He, Min
    Liu, Hui
    Li, Ting
    Lu, Muhan
    Deng, Mingming
    Luo, Gang
    ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2021, 21 (18) : 2525 - 2535
  • [8] Tankyrase inhibitors attenuate WNT/β-catenin signaling and inhibit growth of hepatocellular carcinoma cells
    Ma, Li
    Wang, Xiaolin
    Jia, Tao
    Wei, Wei
    Chua, Mei-Sze
    So, Samuel
    ONCOTARGET, 2015, 6 (28) : 25390 - 25401
  • [9] Disruption of Wnt/β-Catenin Signaling and Telomeric Shortening Are Inextricable Consequences of Tankyrase Inhibition in Human Cells
    Kulak, Ozlem
    Chen, Hua
    Holohan, Brody
    Wu, Xiaofeng
    He, Huawei
    Borek, Dominika
    Otwinowski, Zbyszek
    Yamaguchi, Kiyoshi
    Garofalo, Lauren A.
    Ma, Zhiqiang
    Wright, Woodring
    Chen, Chuo
    Shay, Jerry W.
    Zhang, Xuewu
    Lum, Lawrence
    MOLECULAR AND CELLULAR BIOLOGY, 2015, 35 (14) : 2425 - 2435
  • [10] WNT signaling – lung cancer is no exception
    Judit Rapp
    Luca Jaromi
    Krisztian Kvell
    Gyorgy Miskei
    Judit E. Pongracz
    Respiratory Research, 18
12345