Adiponectin: an enlarging role in acute kidney injury

被引：10
|
作者：
Oh, Jieun [1 ]
Rabb, Hamid [2 ]
机构：
[1] Hallym Univ, Coll Med, Dept Internal Med, Seoul, South Korea
[2] Johns Hopkins Univ, Dept Med, Baltimore, MD 21205 USA
来源：
KIDNEY INTERNATIONAL | 2013年 / 83卷 / 04期
关键词：
ISCHEMIA-REPERFUSION; INFLAMMATION;
D O I：
10.1038/ki.2012.479
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
Adiponectin (APN) is known as an anti-inflammatory adipokine in obesity and atherosclerosis. Jin et al. examine the effects of APN deficiency in renal ischemia/reperfusion injury (IRI) using APN knockout mice and demonstrate that APN deficiency protects mice from IRI. This newly described role for APN in acute kidney injury opens up the possibility of novel mechanistic and therapeutic strategies from the cross-fertilization of the fields of obesity and kidney diseases. Kidney International (2013) 83, 546-548. doi:10.1038/ki.2012.479
引用
收藏
页码：546 / 548
页数：3
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