Serum (1→3)-β-D-Glucan Measurement in Coccidioidomycosis

被引：41

作者：

Thompson, George R., III ^{[1
,2
]}

Bays, Derek J. ^{[1
]}

Johnson, Suzanne M. ^{[1
]}

Cohen, Stuart H. ^{[2
]}

Pappagianis, Demosthenes ^{[1
]}

Finkelman, Malcolm A. ^{[3
]}

机构：

[1] Univ Calif Davis, Dept Med Microbiol & Immunol, Coccidioidomycosis Serol Lab, Davis, CA 95616 USA

[2] Univ Calif Davis, Med Ctr, Dept Internal Med, Div Infect Dis, Sacramento, CA 95817 USA

[3] Associates Cape Cod Inc, E Falmouth, MA USA

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2012年 / 50卷 / 09期

关键词：

INVASIVE FUNGAL-INFECTIONS; SURVEILLANCE NETWORK TRANSNET; BETA-D-GLUCAN; TRANSPLANT RECIPIENTS; DIAGNOSIS; POSADASII; LEUKEMIA; MYCOSIS;

D O I：

10.1128/JCM.00631-12

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The serum (1 -> 3)-beta-D-glucan assay has emerged as an important diagnostic test for invasive fungal disease. The utility of this assay in coccidioidomycosis has not been previously studied. Using a cutoff value of >= 80 pg/ml, we found the sensitivity (43.9%), specificity (91.1%), positive predictive value (81.8%), and negative predictive value (64.1%) to be similar to those of the assay in diagnosing other invasive mycoses.

引用

页码：3060 / 3062

页数：3

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