A single-institution phase II trial of five fractions of radiotherapy followed by four courses of FOLFOX chemotherapy as preoperative therapy for rectal adenocarcinoma.

被引：4
|
作者：
Myerson, Robert J. [1 ]
Parikh, Parag J. [1 ]
Tan, Benjamin [1 ]
Hunt, Steven [1 ]
Fleshman, James W. [1 ]
Birnbaum, Elisa H. [1 ]
Mutch, Matthew G. [1 ]
Kodner, Ira J. [1 ]
Safar, Bashar [1 ]
Naughton, Michael [1 ]
Picus, Joel [1 ]
Sorscher, Steven [1 ]
Lockhart, Albert Craig [1 ]
Rigden, Caron [1 ]
Suresh, Rama [1 ]
Wang-Gillam, Andrea [1 ]
Hall, Lannis [1 ]
机构：
[1] Washington Univ, Sch Med, St Louis, MO USA
来源：
JOURNAL OF CLINICAL ONCOLOGY | 2012年 / 30卷 / 04期
关键词：
D O I：
10.1200/jco.2012.30.4_suppl.553
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
553
引用
收藏
页数：2
相关论文
共 50 条
  • [31] ShorTrip Trial: A Prospective, Multicentric Phase II Single-Arm Trial of Short-Course Radiotherapy Followed by Intensified Consolidation Chemotherapy With the Triplet FOLFOXIRI as Total Neoadjuvant Therapy in Locally Advanced Rectal Cancer
    Borelli, Beatrice
    Conca, Veronica
    Carullo, Martina
    Sainato, Aldo
    Mattioni, Roberto
    Manfredi, Bruno
    Balestri, Riccardo
    Buccianti, Piero
    Morelli, Luca
    Rossi, Piercarlo
    Vagli, Paola
    Prete, Alessandra Anna
    Luca, Frassineti
    Morano, Federica
    Di Donato, Samantha
    Salvatore, Lisa
    Bengala, Carmelo
    Rossini, Daniele
    Boni, Luca
    Antoniotti, Carlotta
    Masi, Gianluca
    Cremolini, Chiara
    Moretto, Roberto
    CLINICAL COLORECTAL CANCER, 2023, 22 (03) : 339 - +
  • [32] Preoperative Short-Course Radiotherapy Followed by Chemotherapy and PD-1 Inhibitor Administration for Locally Advanced Rectal Cancer: The Initial Results of a Randomized Phase II/III Trial (STELLAR II study)
    Tang, Y.
    Zhou, H.
    Hu, C.
    Wei, L.
    Zhang, Y.
    Zhang, W.
    Feng, L.
    Li, N.
    Meng, X.
    Lu, Y.
    Song, Y.
    Qi, S.
    Jing, H.
    Zhai, Y.
    Li, Y.
    Jin, J.
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2024, 120 (02): : E462 - E462
  • [33] Preoperative short-course radiotherapy followed by chemotherapy and PD-1 inhibitor administration for locally advanced rectal cancer: A study protocol of a randomized phase II/III trial (STELLAR II study)
    Zhang, Wenjue
    Tang, Yuan
    Wei, Lichun
    Liu, Shixin
    Wang, Wenling
    Chi, Yihebali
    Wang, Ying
    Kang, Wenyan
    Huang, Wenting
    Deng, Feiyan
    Li, Haoyue
    Ma, Huiying
    Jiang, Liming
    Ding, Zhen
    Feng, Lingling
    Li, Yexiong
    Chen, Yinggang
    Zhou, Haitao
    Hu, Chen
    Jin, Jing
    COLORECTAL DISEASE, 2024, 26 (09) : 1732 - 1740
  • [34] Phase II trial of preoperative combined modality therapy for esophageal carcinoma: Induction cisplatin-irinotecan followed by concurrent cisplatinirinotecan and radiotherapy
    Tew, WP
    Minsky, B
    Bains, M
    Rizk, N
    Rusch, V
    Kelsen, DP
    Shah, M
    Kepler, S
    Gonen, M
    Ilson, DH
    JOURNAL OF CLINICAL ONCOLOGY, 2005, 23 (16) : 312S - 312S
  • [35] Combining chemotherapy and tislelizumab with preoperative split-course hypofraction radiotherapy for locally advanced rectal cancer: study protocol of a prospective, single-arm, phase II trial
    Zheng, Rong
    Wang, Bi-Si
    Li, Zhihua
    Chi, Pan
    Xu, Benhua
    BMJ OPEN, 2023, 13 (03):
  • [36] A phase II trial of escalated dose proton radiotherapy with elective nodal irradiation and concomitant chemotherapy for patients with unresectable, borderline resectable, or medically inoperable pancreatic adenocarcinoma.
    Nichols, Romaine Charles
    Morris, Christopher G.
    Hoppe, Bradford S.
    Rutenberg, Michael Scott
    JOURNAL OF CLINICAL ONCOLOGY, 2017, 35 (04)
  • [37] Upfront radical surgery with total mesorectal excision followed by adjuvant FOLFOX chemotherapy for locally advanced rectal cancer (TME-FOLFOX): an open-label, multicenter, phase II randomized controlled trial
    Lee, Jii Bum
    Kim, Han Sang
    Jung, Inkyung
    Shin, Sang Joon
    Beom, Seung Hoon
    Chang, Jee Suk
    Koom, Woong Sub
    Kim, Tae Il
    Hur, Hyuk
    Min, Byung Soh
    Kim, Nam Kyu
    Park, Sohee
    Jeong, Seung-Yong
    Baek, Jeong-Heum
    Kim, Seon Hahn
    Lim, Joon Seok
    Lee, Kang Young
    Ahn, Joong Bae
    TRIALS, 2020, 21 (01)
  • [38] Upfront radical surgery with total mesorectal excision followed by adjuvant FOLFOX chemotherapy for locally advanced rectal cancer (TME-FOLFOX): an open-label, multicenter, phase II randomized controlled trial
    Jii Bum Lee
    Han Sang Kim
    Inkyung Jung
    Sang Joon Shin
    Seung Hoon Beom
    Jee Suk Chang
    Woong Sub Koom
    Tae Il Kim
    Hyuk Hur
    Byung Soh Min
    Nam Kyu Kim
    Sohee Park
    Seung-Yong Jeong
    Jeong-Heum Baek
    Seon Hahn Kim
    Joon Seok Lim
    Kang Young Lee
    Joong Bae Ahn
    Trials, 21
  • [39] Pathological Results In Locally Advanced Rectal Cancer Treated With Total Neoadjuvant Therapy (TNT) With Short Course Radiotherapy With 25 Gy in 5 Fractions Followed By Chemotherapy With FOLFOX: A Safe And Effective Treatment Strategy
    Gabler, M. C.
    Sole, S.
    Leon, A. E.
    Rubio, G. M.
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2020, 108 (03): : E609 - E609
  • [40] Dose escalation of preoperative short-course radiotherapy followed by neoadjuvant chemotherapy in locally advanced rectal cancer: protocol for an open-label, single-centre, phase I clinical trial
    Zhang, Meng-xia
    Li, Xiao-bo
    Guan, Bing-jie
    Guan, Guo-xian
    Lin, Xiao-yan
    Wu, Xiao-dong
    Chi, Pan
    Xu, Ben-hua
    BMJ OPEN, 2019, 9 (03):
12345