Maternal diet-induced obesity in swine with leptin resistance modifies puberty and pregnancy outputs of the adult offspring

被引：6

作者：

Gonzalez-Bulnes, A. ^{[1
]}

Astiz, S. ^{[1
]}

Sanchez-Sanchez, R. ^{[1
]}

Perez-Solana, M. ^{[1
]}

Gomez-Fidalgo, E. ^{[1
]}

机构：

[1] INIA, Dept Anim Reprod, Madrid 28040, Spain

来源：

JOURNAL OF DEVELOPMENTAL ORIGINS OF HEALTH AND DISEASE | 2013年 / 4卷 / 04期

关键词：

fertility; foetal programming; nutrition; prolificacy; puberty; swine; INTRAUTERINE GROWTH-RETARDATION; REPRODUCTIVE FUNCTION; FEMALE SHEEP; BODY-FAT; UNDERNUTRITION; PIG; ENVIRONMENT; FERTILITY; LIFE; MODELS;

D O I：

10.1017/S2040174413000196

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

The assessment of reproductive features (puberty, fertility and prolificacy) in female Iberian pigs indicates that exposition to intrauterine maternal malnutrition, either by deficiency or excess, is associated with juvenile obesity and a significantly earlier age of puberty onset. At adulthood, prenatal exposition to undernutrition affects reproductive outputs by diminishing prolificacy, an effect that was not found in females exposed to prenatal overnutrition.

引用

页码：290 / 295

页数：6

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