Mediastinal Germ Cell Tumors Updates in Diagnosis and Management

被引：6

作者：

Stram, Amanda R. ^{[1
,2
]}

Kesler, Kenneth A. ^{[3
,4
]}

机构：

[1] Indiana Univ, Dept Surg, Div Cardiothorac Surg, Melvin & Bren Simon Canc Ctr, 545 Barnhill Dr, Indianapolis, IN 46202 USA

[2] Indiana Univ, Dept Surg, Thorac Surg Div, 545 Barnhill Dr, Indianapolis, IN 46202 USA

[3] Indiana Univ, Dept Surg, Div Cardiothorac Surg, Melvin & Bren Simon Canc Ctr, 545 Barnhill Dr EM 212, Indianapolis, IN 46202 USA

[4] Indiana Univ, Dept Surg, Thorac Surg Div, 545 Barnhill Dr EM 212, Indianapolis, IN 46202 USA

来源：

SURGICAL ONCOLOGY CLINICS OF NORTH AMERICA | 2020年 / 29卷 / 04期

关键词：

Germ cell tumors; Mediastinal tumors; Nonseminomatous germ cell cancer; Thoracic surgery; Chemotherapy; RESECTION; CHEMOTHERAPY; EXPERIENCE; SURGERY;

D O I：

10.1016/j.soc.2020.06.005

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Primary mediastinal nonseminomatous germ cell tumors represent a rare but important malignancy that occurs in otherwise young and healthy patients. Treatment is challenging and involves cisplatin-based chemotherapy followed by surgery to remove residual disease. Avoiding bleomycin-containing chemotherapy in the treatment of primary mediastinal nonseminomatous germ cell tumors is important. Prechemotherapy and postchemotherapy pathology as well as postoperative serum tumor markers are independent predictors of long-term survival. © 2020 Elsevier Inc.

引用

页码：571 / 579

页数：9

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