Mediastinal Germ Cell Tumors Updates in Diagnosis and Management

被引：6
|
作者：
Stram, Amanda R. [1 ,2 ]
Kesler, Kenneth A. [3 ,4 ]
机构：
[1] Indiana Univ, Dept Surg, Div Cardiothorac Surg, Melvin & Bren Simon Canc Ctr, 545 Barnhill Dr, Indianapolis, IN 46202 USA
[2] Indiana Univ, Dept Surg, Thorac Surg Div, 545 Barnhill Dr, Indianapolis, IN 46202 USA
[3] Indiana Univ, Dept Surg, Div Cardiothorac Surg, Melvin & Bren Simon Canc Ctr, 545 Barnhill Dr EM 212, Indianapolis, IN 46202 USA
[4] Indiana Univ, Dept Surg, Thorac Surg Div, 545 Barnhill Dr EM 212, Indianapolis, IN 46202 USA
来源：
SURGICAL ONCOLOGY CLINICS OF NORTH AMERICA | 2020年 / 29卷 / 04期
关键词：
Germ cell tumors; Mediastinal tumors; Nonseminomatous germ cell cancer; Thoracic surgery; Chemotherapy; RESECTION; CHEMOTHERAPY; EXPERIENCE; SURGERY;
D O I：
10.1016/j.soc.2020.06.005
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Primary mediastinal nonseminomatous germ cell tumors represent a rare but important malignancy that occurs in otherwise young and healthy patients. Treatment is challenging and involves cisplatin-based chemotherapy followed by surgery to remove residual disease. Avoiding bleomycin-containing chemotherapy in the treatment of primary mediastinal nonseminomatous germ cell tumors is important. Prechemotherapy and postchemotherapy pathology as well as postoperative serum tumor markers are independent predictors of long-term survival. © 2020 Elsevier Inc.
引用
收藏
页码：571 / 579
页数：9
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