Selective and potent benzoxazole inhibitors of Cryptosporidium parvum inosine 5′-monophosphate dehydrogenase

被引：0
|
作者：
Kavitha, Mandapati
Gorla, Suresh Kumar
Zhang, Minjia
Liu, Xiaoping
Sharling, Lisa
Gollapall, Deviprasad R.
Striepen, Boris
Cuny, Gregory D.
Hedstrom, Lizbeth
机构：
[1] Brandeis Univ, Dept Biol, Waltham, MA 02254 USA
[2] Univ Georgia, Ctr Trop & Emerging Global Dis, Athens, GA 30602 USA
[3] Univ Georgia, Dept Cellular Biol, Athens, GA 30602 USA
[4] Harvard Univ, Sch Med, Lab Drug DiscoVery Neurodegenerat, Brigham & Womens Hosp, Cambridge, MA 02138 USA
[5] Brandeis Univ, Dept Chem, Waltham, MA 02254 USA
来源：
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 2010年 / 240卷
关键词：
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
373-MEDI
引用
收藏
页数：1
相关论文
共 50 条
  • [1] Selective and Potent Urea Inhibitors of Cryptosporidium parvum Inosine 5′-Monophosphate Dehydrogenase
    Gorla, Suresh Kumar
    Kavitha, Mandapati
    Zhang, Minjia
    Liu, Xiaoping
    Sharling, Lisa
    Gollapalli, Deviprasad R.
    Striepen, Boris
    Hedstrom, Lizbeth
    Cuny, Gregory D.
    JOURNAL OF MEDICINAL CHEMISTRY, 2012, 55 (17) : 7759 - 7771
  • [2] Optimization of Benzoxazole-Based Inhibitors of Cryptosporidium parvum Inosine 5′-Monophosphate Dehydrogenase
    Gorla, Suresh Kumar
    Kavitha, Mandapati
    Zhang, Minjia
    Chin, James En Wai
    Liu, Xiaoping
    Striepen, Boris
    Makowska-Grzyska, Magdalena
    Kim, Youngchang
    Joachimiak, Andrzej
    Hedstrom, Lizbeth
    Cuny, Gregory D.
    JOURNAL OF MEDICINAL CHEMISTRY, 2013, 56 (10) : 4028 - 4043
  • [3] Highly potent and selective inhibitors for Cryptosporidium parvum inosine 5′-monophosphate dehydrogenase: SAR and anticryptosporidial activity
    Gorla, Suresh K.
    Kavitha, Mandapati
    Zhang, Minjia
    Liu, Xiaoping
    Sharling, Lisa
    MacPherson, Iain S.
    Gollapalli, Deviprasad R.
    Striepen, Boris
    Cuny, Gregory
    Hedstrom, Lizbeth
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2010, 240
  • [4] Triazole Inhibitors of Cryptosporidium parvum Inosine 5′-Monophosphate Dehydrogenase
    Maurya, Sushil K.
    Gollapalli, Deviprasad R.
    Kirubakaran, Shivapriya
    Zhang, Minjia
    Johnson, Corey R.
    Benjamin, Nicole N.
    Hedstrom, Lizbeth
    Cuny, Gregory D.
    JOURNAL OF MEDICINAL CHEMISTRY, 2009, 52 (15) : 4623 - 4630
  • [5] A QSAR model of benzoxazole derivatives as potential inhibitors for inosine 5 '-monophosphate dehydrogenase from Cryptosporidium parvum
    Teotia, Pratibha
    Dwivedi, Surya Prakash
    Dwivedi, Neeraja
    BIOINFORMATION, 2016, 12 (03) : 119 - 123
  • [6] Phthalazinone inhibitors of inosine-5′-monophosphate dehydrogenase from Cryptosporidium parvum
    Johnson, Corey R.
    Gorla, Suresh Kumar
    Kavitha, Mandapati
    Zhang, Minjia
    Liu, Xiaoping
    Striepen, Boris
    Mead, Jan R.
    Cuny, Gregory D.
    Hedstrom, Lizbeth
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2013, 23 (04) : 1004 - 1007
  • [7] Novel adenosine-derived inhibitors of Cryptosporidium parvum inosine 5′-monophosphate dehydrogenase
    Shigetomi, Kengo
    Sarwono, Albertus Eka Yudistira
    Ichikawa, Satoshi
    Ubukata, Makoto
    JOURNAL OF ANTIBIOTICS, 2019, 72 (12): : 934 - 942
  • [8] Novel adenosine-derived inhibitors of Cryptosporidium parvum inosine 5′-monophosphate dehydrogenase
    Kengo Shigetomi
    Albertus Eka Yudistira Sarwono
    Satoshi Ichikawa
    Makoto Ubukata
    The Journal of Antibiotics, 2019, 72 : 934 - 942
  • [9] Repurposing Cryptosporidium Inosine 5′-Monophosphate Dehydrogenase Inhibitors as Potential Antibacterial Agents
    Mandapati, Kavitha
    Gorla, Suresh Kumar
    House, Amanda L.
    McKenney, Elizabeth S.
    Zhang, Minjia
    Rao, Suraj Nagendra
    Gollapalli, Deviprasad R.
    Mann, Barbara J.
    Goldberg, Joanna B.
    Cuny, Gregory D.
    Glomski, Ian J.
    Hedstrom, Lizbeth
    ACS MEDICINAL CHEMISTRY LETTERS, 2014, 5 (08): : 846 - 850
  • [10] QSAR and deep learning model for virtual screening of potential inhibitors against Inosine 5' Monophosphate dehydrogenase (IMPDH) of Cryptosporidium parvum
    Asmare, Misgana Mengistu
    Nitin, Nitin
    Yun, Soon-IL
    Mahapatra, Rajani Kanta
    JOURNAL OF MOLECULAR GRAPHICS & MODELLING, 2022, 111
12345