Polystyrene Nanofiber Materials for Visible-Light-Driven Dual Antibacterial Action via Simultaneous Photogeneration of NO and O2(1Δg)

被引：43
|
作者：
Dolansky, Jiri [1 ,2 ]
Henke, Petr [1 ]
Kubat, Pavel [3 ]
Fraix, Aurore [4 ]
Sortino, Salvatore [4 ]
Mosinger, Jiri [1 ,2 ]
机构：
[1] Charles Univ Prague, Fac Sci, Prague 12843 2, Czech Republic
[2] Czech Acad Sci, Inst Inorgan Chem, Vvi, Rez 25068, Czech Republic
[3] Czech Acad Sci, J Heyrovsky Inst Phys Chem, Vvi, Prague 18223 8, Czech Republic
[4] Univ Catania, Lab Photochem, Dept Drug Sci, I-95125 Catania, Italy
来源：
ACS APPLIED MATERIALS & INTERFACES | 2015年 / 7卷 / 41期
关键词：
nanofiber; singlet oxygen; nitric oxide; photogeneration; antibacterial; NITRIC-OXIDE; SINGLET OXYGEN; PORPHYRIN; PHTHALOCYANINE; POLYMER; PHOTOTHERAPY; AGGREGATION; NANOFABRICS; SCAFFOLD; CELLS;
D O I：
10.1021/acsami.5b06233
中图分类号：
TB3 [工程材料学];
学科分类号：
0805 ; 080502 ;
摘要：
This contribution reports on the preparation, characterization, and biological evaluation of electrospun polystyrene nanofiber materials engineered with a covalently grafted NO photodonor and ionically entangled tetracationic porphyrin, and phthalocyanine photosensitizers. These photofunctional materials exhibit an effective and simultaneous photogeneration of two antibacterial species such as nitric oxide (NO) and singlet oxygen, O-2((1)Delta(g)) under illumination with visible light, as demonstrated by their direct detection using amperometric and time-resolved spectroscopic techniques. Dual-mode photoantibacterial action is demonstrated by antibacterial tests carried out on Escherichia coli.
引用
收藏
页码：22980 / 22989
页数：10
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