Preparation of Avermectin Molecularly Imprinted Polymer Microspheres and Their Adsorption Properties

In this study, avermectin molecularly imprinted microspheres have been prepared by high-temperature thermopolymerization under optimized conditions, employing avermectin as a template molecule, 4-vinylpyridine as a functional monomer, divinylbenzene as a crosslinking agent and azobisisobutyronitrile as an initiator. The interaction between functional monomers and template molecules was investigated by UV/visible and infrared spectroscopies and the adsorption properties of molecularly imprinted polymer and control polymer for avennectin were also comparatively analyzed. The results showed that the adsorption capacity of molecularly imprinted polymer for avermectin was significantly higher than that of the control polymer (P < 0.01), which indicated that the molecularly imprinted polymer microspheres prepared by this method had a specific adsorption effect on the template molecule and that the polymer microspheres could be used to detect and analyze avermectin residues.