Ibogaine related sudden death: A case report

被引:16
|
作者
Papadodima, Stavroula A. [1 ]
Dona, Artemis [1 ]
Evaggelakos, Christos I. [1 ]
Goutas, Nikolaos [1 ]
Athanaselis, Sotirios A. [1 ]
机构
[1] Univ Athens, Sch Med, Dept Forens Med & Toxicol, GR-11527 Athens, Greece
关键词
Ibogaine; Death; Autopsy; Cardiac death; Fatty infiltration of the liver; QT INTERVAL; PROLONGATION;
D O I
10.1016/j.jflm.2013.06.032
中图分类号
DF [法律]; D9 [法律]; R [医药、卫生];
学科分类号
0301 ; 10 ;
摘要
Ibogaine is a naturally occurring alkaloid derived from the roots of the rain forest shrub Tabernanthe iboga. Deaths have occurred temporarily related to the use of ibogaine. However, although not licensed as therapeutic drug, and despite evidence that ibogaine may disturb the rhythm of the heart, this alkaloid is currently used as an anti-addiction drug in alternative medicine for detoxification purposes. We report the case of a man who died suddenly 12-24 h after ibogaine use for alcohol detoxification treatment. In the autopsy liver cirrhosis and heavy fatty infiltration was found. The concentration of ibogaine was 2 mg/l. The potential risks of ibogaine use, especially for persons with pathological medical background, are discussed. (C) 2013 Elsevier Ltd and Faculty of Forensic and Legal Medicine. All rights reserved.
引用
收藏
页码:809 / 811
页数:3
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