HDAC Inhibitors As Novel Targeted Therapies for NUP98-HOXA9 AML Patients

被引:1
|
作者
Rio-Machin, Ana [1 ,2 ]
Gomez-Lopez, Gonzalo [3 ]
Maiques-Diaz, Alba [2 ]
Alvarez, Sara [2 ]
Calasanz, Maria Jose [4 ]
Fitzgibbon, Jude [1 ]
Cigudosa, Juan C. [2 ]
机构
[1] Queen Mary Univ London, Barts Canc Inst, Ctr Haematooncol, London, England
[2] Ctr Nacl Invest Oncol, Mol Cytogenet Grp, Human Canc Genet Programme, Madrid, Spain
[3] Ctr Nacl Invest Oncol, Bioinformat Unit, Madrid, Spain
[4] Univ Navarra, Sch Med, Dept Genet, IDISNA, Pamplona, Spain
关键词
D O I
10.1182/blood.V128.22.2685.2685
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
2685
引用
收藏
页数:4
相关论文
共 50 条
  • [31] NUP98-HOXA9融合基因阳性儿童急性髓细胞白血病1例报告
    郭巍巍
    刘斌
    李伟京
    赵晓曦
    高超
    中国小儿血液与肿瘤杂志, 2015, 20 (03) : 153 - 154
  • [32] The oncogenic properties of the NUP98-HOXA9 fusion protein: Nucleoporin-specific FG repeats as well as the HOXA9 homeodomain and PBX interaction motif are essential.
    vanDeursen, J
    Kasper, LH
    Pritchard, C
    Schnabel, CA
    Cleary, M
    BLOOD, 1997, 90 (10) : 1446 - 1446
  • [33] CREB binding protein interacts with nucleoporin-specific FG repeats that activate transcription and mediate NUP98-HOXA9 oncogenicity
    Kasper, LH
    Brindle, PK
    Schnabel, CA
    Pritchard, CEJ
    Cleary, ML
    van Deursen, JMA
    MOLECULAR AND CELLULAR BIOLOGY, 1999, 19 (01) : 764 - 776
  • [34] MLL Is Essential for NUP98-HOXA9-Induced Leukemia
    Shima, Yutaka
    Yumoto, Minori
    Kitabayashi, Issay
    BLOOD, 2015, 126 (23)
  • [35] MLL is essential for NUP98-HOXA9-induced leukemia
    Shima, Y.
    Yumoto, M.
    Katsumoto, T.
    Kitabayashi, I.
    LEUKEMIA, 2017, 31 (10) : 2200 - 2210
  • [36] MLL is essential for NUP98-HOXA9-induced leukemia
    Y Shima
    M Yumoto
    T Katsumoto
    I Kitabayashi
    Leukemia, 2017, 31 : 2200 - 2210
  • [37] Chromatin-prebound Crm1 recruits Nup98-HoxA9 fusion to induce aberrant expression of Hox cluster genes
    Oka, Masahiro
    Mura, Sonoko
    Yamada, Kohji
    Sangel, Percival
    Hirata, Saki
    Maehara, Kazumitsu
    Kawakami, Koichi
    Tachibana, Taro
    Ohkawa, Yasuyuki
    Kimura, Hiroshi
    Yoneda, Yoshihiro
    ELIFE, 2016, 5
  • [38] Novel FLT3 Inhibitors and Targeted Therapies in AML
    Levis, M.
    ANNALS OF HEMATOLOGY, 2015, 94 (SUPPL 1) : 35 - 37
  • [39] Novel FLT3 Inhibitors and Targeted Therapies in AML
    Levis, M.
    ANNALS OF HEMATOLOGY, 2015, 94 : S35 - S37
  • [40] NUP98-HOXA9 induces long-term proliferation and blocks differentiation of primary human CD34+ hematopoietic cells
    Takeda, Akiko
    Goolsby, Charles
    Yaseen, Nabeel R.
    CANCER RESEARCH, 2006, 66 (13) : 6628 - 6637