VHL gene alterations promote cancer progression in early-stage clear cell renal carcinoma through nuclear localization of hypoxia-indoucible factor-1A

被引:0
|
作者
Di Cristofano, C. [1 ]
Minervini, A. [2 ]
Leopizzi, M. [1 ]
Lessi, F. [3 ]
Menicagli, M. [4 ]
Salinitri, G. [3 ]
Bertacca, G. [3 ]
Pefanis, G. [3 ]
Masieri, L. [2 ]
Collecchi, P. [3 ]
Petrozza, V. [2 ]
Della Rocca, C. [2 ]
Minervini, R. [3 ]
Carini, M. [2 ]
Cavazzana, A. [3 ]
Bevilacqua, G. [3 ]
机构
[1] Univ Roma La Sapienza, Polo Pontino, Italy
[2] Univ Florence, Careggi Hosp, I-50121 Florence, Italy
[3] Univ Hosp Pisa, Pisa, Italy
[4] Inst Mol Genet & Med, Pisa, Italy
关键词
D O I
暂无
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
621
引用
收藏
页码:271 / 271
页数:1
相关论文
共 29 条
  • [21] Positive feedback loop and synergistic effects between hypoxia-inducible factor-2 and stearoylCoA desaturase-1 promote tumorigenesis in clear cell renal cell carcinoma
    Zhang, Yujian
    Wang, Hui
    Zhang, Jin
    Lv, Jianwei
    Huang, Yiran
    CANCER SCIENCE, 2013, 104 (04) : 416 - 422
  • [22] Identification of CDCP1 as a hypoxia-inducible factor 2α (HIF-2α) target gene that is associated with survival in clear cell renal cell carcinoma patients
    Emerling, Brooke M.
    Benes, Cyril H.
    Poulogiannis, George
    Bell, Eric L.
    Courtney, Kevin
    Liu, Hui
    Choo-Wing, Rayman
    Bellinger, Gary
    Tsukazawa, Kazumi S.
    Brown, Victoria
    Signoretti, Sabina
    Soltoff, Stephen P.
    Cantley, Lewis C.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2013, 110 (09) : 3483 - 3488
  • [23] Association of hypoxia-inducible factor-1α (HIF1α) 1772C/T gene polymorphism with susceptibility to renal cell carcinoma/prostate cancer
    Li, Hongyan
    Liao, Chunling
    Weng, Wenjuan
    Zhong, Hongzhen
    Zhou, Tianbiao
    BIOCELL, 2020, 44 (02) : 257 - 262
  • [24] Chondromodulin-1 and vascular endothelial growth factor-A expression in esophageal squamous cell carcinoma: accelerator and brake theory for angiogenesis at the early stage of cancer progression
    Youichi Kumagai
    Tetsuhiko Tachikawa
    Morihiro Higashi
    Jun Sobajima
    Akemi Takahashi
    Kunihiko Amano
    Kei-ichiro Ishibashi
    Erito Mochiki
    Koji Yakabi
    Jun-ichi Tamaru
    Hideyuki Ishida
    Esophagus, 2020, 17 : 159 - 167
  • [25] Chondromodulin-1 and vascular endothelial growth factor-A expression in esophageal squamous cell carcinoma: accelerator and brake theory for angiogenesis at the early stage of cancer progression
    Kumagai, Youichi
    Tachikawa, Tetsuhiko
    Higashi, Morihiro
    Sobajima, Jun
    Takahashi, Akemi
    Amano, Kunihiko
    Ishibashi, Kei-Ichiro
    Mochiki, Erito
    Yakabi, Koji
    Tamaru, Jun-Ichi
    Ishida, Hideyuki
    ESOPHAGUS, 2020, 17 (02) : 159 - 167
  • [26] Identification of CDCP1 as a hypoxia-inducible factor 2α (HIF-2α) target gene that is associated with survival in clear cell renal cell carcinoma patients (vol 110, pg 3483, 2013)
    Emerling, Brooke M.
    Benes, Cyril H.
    Poulogiannis, George
    Bell, Eric L.
    Courtney, Kevin
    Liu, Hui
    Choo-Wing, Rayman
    Bellinger, Gary
    Tsukazawa, Kazumi S.
    Brown, Victoria
    Signoretti, Sabina
    Soltoff, Stephen P.
    Cantley, Lewis C.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 118 (32)
  • [27] The relationship of erythropoietin overexpression with von Hippel-Lindau tumour suppressor gene mutations between hypoxia-inducible factor-1α and-2α in sporadic clear cell renal carcinoma
    Gong, Kan
    Zhang, Ning
    Zhang, Kai
    Na, Yanqun
    INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2010, 26 (06) : 907 - 912
  • [28] Association of hypoxia-inducible factor-1α (HIF1α) 1790G/A gene polymorphism with renal cell carcinoma and prostate cancer susceptibility: a meta-analysis
    Li, Hong-Yan
    Zhou, Tianbiao
    Lin, Wenshan
    Lin, Shujun
    Zhong, Hongzhen
    BMC MEDICAL GENETICS, 2019, 20 (01)
  • [29] Anterior gradient 2 promotes tumorigenesis through upregulation of CCAAT-enhancer binding protein beta and hypoxia-inducible factor-2α and subsequent secretion of interleukin-6, interleukin-8, and vascular endothelial growth factor in the Caki-1 clear cell renal cell carcinoma cell line
    Pajdzik, Kinga
    Wilamowski, Mateusz
    Zurawek, Dariusz
    Stopa, Kinga B.
    Nodzynski, Michal
    Kalita, Agata
    Jura, Jolanta
    IUBMB LIFE, 2020, 72 (08) : 1807 - 1818