Comparing the Increased Intracranial Volume From Different Surgical Methods for Syndromic Craniosynostosis

Purpose: Fronto-orbital advancement (FOA) is the traditional surgical method used to increase intracranial volume, but posterior cranial vault distraction osteogenesis (PVDO) has been gaining popularity as an initial treatment option. This study aimed to compare the effects of FOA and PVDO on intracranial volume. Patients and Methods: Sixteen patients with multiple-suture synostosis and severe intracranial volume restriction were treated with FOA or PVDO at Children's Hospital of Fudan University between January 2016 and December 2019. Data on age at surgery, sex, preoperative intracranial volume, and postoperative intracranial volume were collected. Results: Seven patients underwent FOA and 9 underwent PVDO. All patients underwent surgery for the first time, and the surgeries were performed by the same physician. There was no statistically significant difference in age at surgery or in the intracranial volumes before and after surgery between the 2 groups (P>0.05). There was a statistically significant difference in the intracranial volume changes between the 2 groups before and after surgery (P=0.028). Conclusions: Posterior cranial vault distraction osteogenesis provided statistically greater intracranial volume expansion than FOA.