机构:
Matsumoto Dent Univ, Hard Tissue Pathol Unit, Grad Sch Oral Med, Shiojiri, JapanStomatol Hosp Shenyang, Dept Orthodont, Shenyang 110002, Peoples R China
The expression of TRAF6 protein and TRAF6 mRNA during different stages of deciduous tooth root physiological absorption was observed. Deciduous teeth with physiological absorption period were divided into 3 groups according to the length of deciduous tooth root absorption: early stage of deciduous tooth root physiological absorption (I group), intermediate stage of deciduous teeth roots' physiological absorption (II group), final stage of deciduous tooth root physiological absorption (III group). TRAF6 antibody and TRAF6 hybridization in situ agent were used to detect the expression of TRAF6 protein and TRAF6 mRNA of odontoclasts of deciduous teeth with different physiological absorption stages. Im-pro-plas 6.0 analytical system software was used to measure the optical density of odontoclasts stained in three groups. SPSS13.0 software was used to analyze the regularity of expression. Optical density value of TRAF6 immunohistochemistry stain and TRAF6 mRNA in situ hybridization stain of odontoclasts was larger in I and II group compared with the value in III group. It indicated that odontoclasts in early and intermediate stages showed more activity than in the final stage. Expression of TRAF6 protein and TRAF6 mRNA during different stages of deciduous tooth root physiological absorption was consistent with the activity of odontoclast.
机构:
Harvard Med Sch, Dept Biol Chem & Mol Pharmacol, Boston, MA 02115 USA
Boston Childrens Hosp, Program Cellular & Mol Med, Boston, MA 02115 USAHarvard Med Sch, Dept Biol Chem & Mol Pharmacol, Boston, MA 02115 USA
Fu, Tian-Min
Shen, Chen
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Harvard Med Sch, Dept Biol Chem & Mol Pharmacol, Boston, MA 02115 USA
Boston Childrens Hosp, Program Cellular & Mol Med, Boston, MA 02115 USAHarvard Med Sch, Dept Biol Chem & Mol Pharmacol, Boston, MA 02115 USA
Shen, Chen
Li, Qiubai
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Harvard Med Sch, Dept Biol Chem & Mol Pharmacol, Boston, MA 02115 USA
Boston Childrens Hosp, Program Cellular & Mol Med, Boston, MA 02115 USAHarvard Med Sch, Dept Biol Chem & Mol Pharmacol, Boston, MA 02115 USA
Li, Qiubai
Zhang, Pengfei
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Harvard Med Sch, Dept Biol Chem & Mol Pharmacol, Boston, MA 02115 USA
Boston Childrens Hosp, Program Cellular & Mol Med, Boston, MA 02115 USAHarvard Med Sch, Dept Biol Chem & Mol Pharmacol, Boston, MA 02115 USA
Zhang, Pengfei
Wu, Hao
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Harvard Med Sch, Dept Biol Chem & Mol Pharmacol, Boston, MA 02115 USA
Boston Childrens Hosp, Program Cellular & Mol Med, Boston, MA 02115 USAHarvard Med Sch, Dept Biol Chem & Mol Pharmacol, Boston, MA 02115 USA
机构:
Sun Yat Sen Univ, State Key Lab Biocontrol, Guangzhou 510275, Guangdong, Peoples R ChinaSun Yat Sen Univ, State Key Lab Biocontrol, Guangzhou 510275, Guangdong, Peoples R China
Li, Yingqiu
Xie, Ji-Ji
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Sun Yat Sen Univ, State Key Lab Biocontrol, Guangzhou 510275, Guangdong, Peoples R ChinaSun Yat Sen Univ, State Key Lab Biocontrol, Guangzhou 510275, Guangdong, Peoples R China