Expression of TRAF6 Protein and TRAF6 mRNA during Different Stages of Deciduous Tooth Root Physiological Absorption

被引:0
|
作者
Zhang, Guirong [1 ]
Zhou, Linxi [2 ]
Ito, Koji [3 ]
Sugita, Yoshihiko [3 ]
Nakano, Keisuke [4 ]
Maeda, Hatsuhiko [3 ]
Wang, Xue [1 ]
Wang, Minghua [1 ]
机构
[1] Stomatol Hosp Shenyang, Dept Orthodont, Shenyang 110002, Peoples R China
[2] Shanghai Jiao Tong Univ, Coll Stomatol, Shanghai 200030, Peoples R China
[3] Aichi Gakuin Univ, Sch Dent, Dept Oral Pathol, Nagoya, Aichi 464, Japan
[4] Matsumoto Dent Univ, Hard Tissue Pathol Unit, Grad Sch Oral Med, Shiojiri, Japan
关键词
Odontoclast; TRAF6; TRAP; mRNA; Root physiological absorption; RESISTANT ACID-PHOSPHATASE; BONE-RESORPTION; TEETH;
D O I
暂无
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
The expression of TRAF6 protein and TRAF6 mRNA during different stages of deciduous tooth root physiological absorption was observed. Deciduous teeth with physiological absorption period were divided into 3 groups according to the length of deciduous tooth root absorption: early stage of deciduous tooth root physiological absorption (I group), intermediate stage of deciduous teeth roots' physiological absorption (II group), final stage of deciduous tooth root physiological absorption (III group). TRAF6 antibody and TRAF6 hybridization in situ agent were used to detect the expression of TRAF6 protein and TRAF6 mRNA of odontoclasts of deciduous teeth with different physiological absorption stages. Im-pro-plas 6.0 analytical system software was used to measure the optical density of odontoclasts stained in three groups. SPSS13.0 software was used to analyze the regularity of expression. Optical density value of TRAF6 immunohistochemistry stain and TRAF6 mRNA in situ hybridization stain of odontoclasts was larger in I and II group compared with the value in III group. It indicated that odontoclasts in early and intermediate stages showed more activity than in the final stage. Expression of TRAF6 protein and TRAF6 mRNA during different stages of deciduous tooth root physiological absorption was consistent with the activity of odontoclast.
引用
收藏
页码:1 / 6
页数:6
相关论文
共 50 条
  • [1] Expression of TRAF6 mRNA on the Resorbed Surface of Deciduous Teeth Root
    Zhang, Guirong
    Nakano, Keisuke
    Honda, Yuma
    Wang, Xue
    Wang, Minghua
    Xu, Yan
    Kawakami, Toshiyuki
    JOURNAL OF HARD TISSUE BIOLOGY, 2011, 20 (03) : 177 - 183
  • [2] NUMBL interacts with TRAF6 and promotes the degradation of TRAF6
    Zhou, Li
    Ma, Qi
    Shi, Huili
    Huo, Keke
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2010, 392 (03) : 409 - 414
  • [3] Why are the phenotypes of TRAF6 knock-in and TRAF6 knock-out mice so different?
    Petrova, Tsvetana
    Bennett, Kyle
    Nanda, Sambit
    Strickson, Sam
    Scudamore, Cheryl L.
    Prescott, Alan R.
    Cohen, Philip
    PLOS ONE, 2022, 17 (02):
  • [4] TRAF6 distributes tolerance
    Karen Honey
    Nature Reviews Immunology, 2005, 5 : 269 - 269
  • [5] Traf6 is essential for murine tooth cusp morphogenesis
    Ohazama, A
    Courtney, JM
    Tucker, AS
    Naito, A
    Tanaka, S
    Inoue, JI
    Sharpe, PT
    DEVELOPMENTAL DYNAMICS, 2004, 229 (01) : 131 - 135
  • [6] Kaempferol attenuates streptozotocin-induced diabetic nephropathy by downregulating TRAF6 expression: The role of TRAF6 in diabetic nephropathy
    Luo, Wu
    Chen, Xiaojun
    Ye, Lin
    Chen, Xuemei
    Jia, Wenjing
    Zhao, Yanni
    Samorodov, Aleksandr, V
    Zhang, Yali
    Hu, Xueting
    Zhuang, Fei
    Qian, Jianchang
    Zheng, Chao
    Liang, Guang
    Wang, Yi
    JOURNAL OF ETHNOPHARMACOLOGY, 2021, 268
  • [7] Different Activation of TRAF4 and TRAF6 in Inflammatory Bowel Disease
    Shen, Jun
    Qiao, Yuqi
    Ran, Zhihua
    Wang, Tianrong
    MEDIATORS OF INFLAMMATION, 2013, 2013
  • [8] The relationship between TRAF6 and tumors
    Jiaoduan Li
    Nian Liu
    Ling Tang
    Bei Yan
    Xiang Chen
    Jianglin Zhang
    Cong Peng
    Cancer Cell International, 20
  • [9] TRAF6 and motor neuron loss
    Butler, Carrie Lynn
    Dennis, John S.
    Kane, Michael J.
    Citron, Bruce A.
    FASEB JOURNAL, 2009, 23
  • [10] Role of TRAF6 in the immune system
    Choi, YW
    MECHANISMS OF LYMPHOCYTE ACTIVATION AND IMMUNE REGULATION X: INNATE IMMUNITY, 2005, 560 : 77 - 82