Approaches for Specific Knock-down of UDP-GlcNAc 2-Epimerase/ManNAc Kinase (GNE), the Key Enzyme of Sialic Acid Biosynthesis

被引：0

作者：

Moeller, Heinz ^{[1
]}

Reinke, Stefan O. ^{[1
]}

Hinderlich, Stephan ^{[1
]}

机构：

[1] Univ Appl Sci, Berlin, Germany

来源：

GLYCOBIOLOGY | 2008年 / 18卷 / 11期

关键词：

D O I：

暂无

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

241

引用

页码：999 / 1000

页数：2

共 47 条

[41] Molecular cloning of the rate-limiting enzyme in sialic acid synthesis, uridinediphosphate-N-acetylglucosamine-2-epimerase (UDP-GlcNAc-2-epimerase): Implications for sialuria.
Seppala, R
Lehto, VP
Gahl, WA
AMERICAN JOURNAL OF HUMAN GENETICS, 1997, 61 (04) : A261 - A261
[42] A bifunctional enzyme catalyzes the first two steps in N-acetylneuraminic acid biosynthesis of rat liver - Purification and characterization of UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase
Hinderlich, S
Stasche, R
Zeitler, R
Reutter, W
JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (39) : 24313 - 24318
[43] Molecular characterization of pig UDP-N-acetylglucosamine-2-epimerase/N-acetylmannosamine kinase (Gne) gene:: Effect of dietary sialic acid supplementation on gene expression in piglets
Wang, Bing
Hu, Honghua
Yu, Bing
Troy, Frederic A., II
CURRENT TOPICS IN NUTRACEUTICAL RESEARCH, 2007, 5 (04) : 165 - 175
[44] New UDP-GlcNAc C4 epimerase involved in the biosynthesis of 2-acetamino-2-deoxy-L-altruronic acid in the O-antigen repeating units of Plesiomonas shigelloides O17
Kowal, P
Wang, PG
BIOCHEMISTRY, 2002, 41 (51) : 15410 - 15414
[45] New UDP-GlcNAc C4 epimerase involved in the biosynthesis of 2-acetamino-2-deoxy-L-altruronic acid in the O-antigen repeating units of plesiomonas shigelloides O17.
Kowal, P
Wang, PG
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2002, 224 : U267 - U267
[46] A bifunctional enzyme catalyzes the first two steps in N-acetylneuraminic acid biosynthesis of rat liver - Molecular cloning and functional expression of UDP-N-acetyl-glucosamine 2-epimerase/N-acetylmannosamine kinase
Stasche, R
Hinderlich, S
Weise, C
Effertz, K
Lucka, L
Moormann, P
Reutter, W
JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (39) : 24319 - 24324
[47] Primary structure and expression analysis of human UDP-N-acetyl-glucosamine-2-epimerase/N-acetylmannosamine kinase, the bifunctional enzyme in neuraminic acid biosynthesis
Lucka, L
Krause, M
Danker, K
Reutter, W
Horstkorte, R
FEBS LETTERS, 1999, 454 (03) : 341 - 344

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