Anti-tumor activity of elacestrant (RAD1901) in combination with alpelisib (BYL-719) in patient-derived xenograft models of ER plus breast cancer

被引：0
|
作者：
Sankaran, Banu
Garner, Fiona
Hattersley, Gary
Purandare, Dinesh
Bihani, Teeru
机构：
[1] Novartis, Cambridge, MA USA
[2] Radius Hlth, Waltham, MA USA
来源：
CANCER RESEARCH | 2018年 / 78卷 / 04期
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
P4-04-14
引用
收藏
页数：1
相关论文
共 50 条
  • [41] Selinexor demonstrates anti-tumor efficacy in paired patient-derived xenograft models and hydrogel-embedded histoculture drug sensitivity test of penile cancer
    He, Yuanqiao
    Mei, Jiaqi
    Hao, Hua
    Liu, Fanrong
    Yi, Yun
    Hu, Chao
    Zou, Fangxing
    Lu, Xiongbing
    JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 2023, 149 (10) : 6931 - 6941
  • [42] Preclinical anti-tumor efficacy of FGFR2-ADC BAY 1187982 in patient-derived gastric, breast and ovarian cancer models
    Sommer, Anette
    Kopitz, Charlotte
    Schatz, Christoph
    Zierz, Ruprecht
    Schuhmacher, Joachim
    Wittemer-Rump, Sabine
    Prins, Klaas
    Braun, Manuela
    Reetz, Frank
    Kreft, Bertolt
    Huynh, Hung T.
    Ziegelbauer, Karl
    CANCER RESEARCH, 2015, 75
  • [43] Anti-tumor activity of Debio 0123 in combination with sacituzumab govitecan in preclinical models of breast cancer
    Piggott, Luke
    Imedio, Esteban Rodrigo
    Staehli, Francesco
    CANCER RESEARCH, 2024, 84 (06)
  • [44] The MAT2A inhibitor, AG-270, combines with both taxanes and gemcitabine to yield enhanced anti-tumor activity in patient-derived xenograft models
    Hyer, Marc L.
    Kalev, Peter
    Fletcher, Mark
    Chen, Chi-Chao
    Aguado-Fraile, Elia
    Mandley, Everton
    Newhouse, Sheila
    Lein, Max
    Nagaraja, Raj
    Tuncay, Yesim
    Murtie, Josh
    Marks, Kevin M.
    Marjon, Katya
    CANCER RESEARCH, 2020, 80 (16)
  • [45] Evaluation of Trastuzumab Anti-Tumor Efficacy and its Correlation with HER-2 Status in Patient-Derived Gastric Adenocarcinoma Xenograft Models
    Chen, Hao
    Ye, Qingqing
    Lv, Jing
    Ye, Peng
    Sun, Yun
    Fan, Shuqiong
    Su, Xinying
    Gavine, Paul
    Yin, Xiaolu
    PATHOLOGY & ONCOLOGY RESEARCH, 2015, 21 (04) : 947 - 955
  • [46] Tumor shedding and metastatic progression after tumor excision in patient-derived orthotopic xenograft models of triple-negative breast cancer
    Aryana M. Razmara
    Elodie Sollier
    Grace N. Kisirkoi
    Sam W. Baker
    Margot B. Bellon
    Alex McMillan
    Clementine A. Lemaire
    Vishnu C. Ramani
    Stefanie S. Jeffrey
    Kerriann M. Casey
    Clinical & Experimental Metastasis, 2020, 37 : 413 - 424
  • [47] Tumor shedding and metastatic progression after tumor excision in patient-derived orthotopic xenograft models of triple-negative breast cancer
    Razmara, Aryana M.
    Sollier, Elodie
    Kisirkoi, Grace N.
    Baker, Sam W.
    Bellon, Margot B.
    McMillan, Alex
    Lemaire, Clementine A.
    Ramani, Vishnu C.
    Jeffrey, Stefanie S.
    Casey, Kerriann M.
    CLINICAL & EXPERIMENTAL METASTASIS, 2020, 37 (03) : 413 - 424
  • [48] Pharmacological eIF4E inhibition suppresses anti-tumor activity in ER plus breast cancer
    Friedersdorf, Matthew
    Blake, Devon
    Thompson, Sarah
    Marran, Krista
    Sorrentino, Jessica
    CANCER RESEARCH, 2024, 84 (09)
  • [49] MP0250, a VEGF and HGF neutralizing DARPin® molecule shows high anti-tumor efficacy in mouse xenograft and patient-derived tumor models
    Fiedler, Ulrike
    Ekawardhani, Savira
    Cornelius, Andreas
    Gilboy, Pat
    Bakker, Talitha R.
    Dolado, Ignacio
    Stumpp, Michael T.
    Dawson, Keith M.
    ONCOTARGET, 2017, 8 (58) : 98371 - 98383
  • [50] RAD140, an orally available selective androgen receptor modulator, inhibits the growth of AR/ER positive breast cancer cell line- and patient-derived xenograft models
    Yu, Ziyang
    He, Suqin
    Brown, Jeffrey
    Miller, Chris
    Saeh, Jamal
    Hattersley, Gary
    CANCER RESEARCH, 2017, 77
12345